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Patent Assignment Assignor Details

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Assignor Name : ADVANCED BIOHEALING, INC.

Total Assignments: 6

Assignment: 1

Reel/Frame:	017882/0698			Pages:	9
		Recorded:	07/05/2006
Conveyance:	SECURITY AGREEMENT

Assignor

ADVANCED BIOHEALING, INC.

Exec Dt:

05/25/2006

Assignees

SMITH & NEPHEW WOUND MANGEMENT (LA JOLLA)

15 ADAM STREET

LONDON, ENGLAND WC2N6LA

SMITH & NEPHEW, INC.

1450 BROOKS ROAD

MEMPHIS, TENNESSEE 38116

Properties

Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #
4721096	NONE		07036154	5266480	NONE		07575518	5478739	NONE		07965476
5460939	NONE		08200140	5512475	NONE		08418230	5518915	NONE		08418239
5830708	NONE		08470101	5843766	NONE		08597053	5763267	NONE		08632972
5858721	NONE		08978520	6291240	NONE		09137567	6284284	NONE		09182822
6381981	NONE		09847902	NONE	US20040180431		10805774	NONE	US20040259190		10851773

Correspondence name and address
	BARBARA ALDER
	PAUL, HASTINGS, JANOFSKY & WALKER LLP
	695 TOWN CENTER DRIVE, 17TH FLOOR
	COSTA MESA, CA 92626

Assignment: 2

Reel/Frame:	018313/0385			Pages:	35
		Recorded:	09/15/2006
Conveyance:	SECURITY AGREEMENT

Assignor

ADVANCED BIOHEALING, INC.

Exec Dt:

09/14/2006

Assignee

CANAAN VII L.P., AS ADMINISTRATIVE AGENT

105 ROWAYTON AVENUE

ATTN: DR. STEPHEN BLOCH

ROWAYTON, CONNECTICUT 06853

Properties

Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #
4721096	NONE		07036154	4963489	NONE		07242096	5266480	NONE		07575518
5478739	NONE		07965476	5443950	NONE		08131361	5460939	NONE		08200140
5512475	NONE		08418230	5518915	NONE		08418239	5830708	NONE		08470101
5843766	NONE		08597053	5763267	NONE		08632972	6548297	NONE		08817864
5858721	NONE		08978520	6291240	NONE		09137567	6284284	NONE		09182822
6541028	NONE		09341733	6713084	NONE		09341745	6381981	NONE		09847902
6582696	US20020192197		10175939	6962775	US20020192191		10176212	0259190	NONE		UNAVAILABLE
0180431	NONE		UNAVAILABLE

Correspondence name and address
	LEBOEUF, LAMB, GREENE & MACRAE LLP
	ATTN: J. DORMER STEPHEN
	225 ASYLUM ST., 13TH FLOOR
	HARTFORD, CT 06103

Assignment: 3

Reel/Frame:	018806/0123			Pages:	5
		Recorded:	01/19/2007
Conveyance:	SECURITY AGREEMENT

Assignor

ADVANCED BIOHEALING, INC.

Exec Dt:

12/21/2006

Assignee

HORIZON TECHNOLOGY FUNDING COMPANY LLC

76 BATTERSON PARK ROAD

FARMINGTON, CONNECTICUT 06032

Properties

Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #
4963489	NONE		07242096	5266480	NONE		07575518	5478739	NONE		07965476
5443950	NONE		08131361	5460939	NONE		08200140	5512475	NONE		08418230
5518915	NONE		08418239	5830708	NONE		08470101	5843766	NONE		08597053
5763267	NONE		08632972	6548297	NONE		08817864	6291240	NONE		09137567
6284284	NONE		09182822	6541028	NONE		09341733	6713084	NONE		09341745
6381981	NONE		09847902	6582696	US20020192197		10175939	6962775	US20020192191		10176212
NONE	US20040180431		10805774	NONE	US20040259190		10851773

Correspondence name and address
	JOHN C. BOMBARA
	HORIZON TECHNOLOGY FINANCE, LLC
	76 BATTERSON PARK
	FARMINGTON, CT 06032

Assignment: 4

Reel/Frame:	019489/0951			Pages:	4
		Recorded:	06/25/2007
Conveyance:	RELEASE OF SECURITY

Assignor

ADVANCED BIOHEALING, INC.

Exec Dt:

06/19/2007

Assignee

CANAAN VII L.P., AS ADMINISTRATION AGENT

285 RIVERSIDE AVENUE, SUITE 250

ATTN: DR. SETEPHEN BLOCH

WESTPORT, CONNECTICUT 06880

Properties

Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #
4721096	NONE		07036154	4963489	NONE		07242096	5266480	NONE		07575518
5478739	NONE		07965476	5443950	NONE		08131361	5460939	NONE		08200140
5512475	NONE		08418230	5518915	NONE		08418239	5830708	NONE		08470101
5843766	NONE		08597053	5763267	NONE		08632972	6548297	NONE		08817864
5858721	NONE		08978520	6291240	NONE		09137567	6284284	NONE		09182822
6541028	NONE		09341733	6713084	NONE		09341745	6381981	NONE		09847902
6582696	US20020192197		10175939	6962775	US20020192191		10176212

Correspondence name and address
	LEBOEUF, LAMB, GREENE & MACRAE LLP
	ATTN: J. DORMER STEPHEN
	225 ASYLUM STREET
	13TH FLOOR
	HARTFORD, CT 06103

Assignment: 5

Reel/Frame:	020270/0150			Pages:	2
		Recorded:	12/19/2007
Attorney Dkt #:	A0831.90009US00
Conveyance:	ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS).

Assignor

ADVANCED BIOHEALING, INC.

Exec Dt:

11/29/2007

Assignee

SMITH & NEPHEW, INC.

1450 BROOKS ROAD

MEMPHIS, TENNESSEE 38116

Properties

Pat #

Pub #

Intl #

App #

Pat #

Pub #

Intl #

App #

5478739

NONE

07965476

NONE

US20040180431

10805774

Correspondence name and address
	WOLF, GREENFIELD & SACKS, P.C.
	600 ATLANTIC AVENUE
	BOSTON, MA 02210

Assignment: 6

Reel/Frame:	030130/0385			Pages:	4
		Recorded:	04/02/2013
Attorney Dkt #:	A0831.90000US00
Conveyance:	CHANGE OF NAME (SEE DOCUMENT FOR DETAILS).

Assignor

ADVANCED BIOHEALING, INC.

Exec Dt:

07/18/2012

Assignee

SHIRE REGENERATIVE MEDICINE, INC.

11095 TORREYANA ROAD

SAN DIEGO, CALIFORNIA 92121

Properties

Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #
5512475	NONE		08418230	5518915	NONE		08418239	5830708	NONE		08470101
5843766	NONE		08597053	5763267	NONE		08632972	6548297	NONE		08817864
6291240	NONE		09137567	6284284	NONE		09182822	6541028	NONE		09341733
6713084	NONE		09341745	6381981	NONE		09847902	6582696	US20020192197		10175939
6962775	US20020192191		10176212	NONE	US20110245929		13042295

Correspondence name and address
	WOLF, GREENFIELD & SACKS, P.C.
	600 ATLANTIC AVENUE
	BOSTON, MA 02210

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