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Patent Assignment Assignor Details

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Assignor Name : VERTEX PHARMACEUTICALS INCORPORATED

Total Assignments: 66

Assignment: 1

Reel/Frame:	013767/0611			Pages:	14
		Recorded:	06/30/2003
Conveyance:	ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS).

Assignors

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

03/28/2003

VERTEX PHARMACEUTICALS LLC

Exec Dt:

03/28/2003

PANVERA LLC

Exec Dt:

03/28/2003

Assignee

INVITROGEN CORPORATION

1600 FARADAY AVENUE

CARLSBAD, CALIFORNIA 92008

Properties

Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #
5786139	NONE		08353079	5824557	NONE		08626520	6124128	NONE		08706408
5981200	NONE		08792553	6004808	NONE		08878801	5891696	NONE		08904376
6054321	NONE		08911825	NONE	US20010004522		08959367	6077707	NONE		08974737
6284461	NONE		09067612	6200762	NONE		09118497	6214563	NONE		09120516
6221612	NONE		09122477	6031094	NONE		09128679	6495664	NONE		09129192
6107477	NONE		09167040	6100039	NONE		09239355	6143492	NONE		09301395
6420130	NONE		09301525	6410255	NONE		09306542	6319678	NONE		09344995
6551790	US20020076740		09455202	6514687	NONE		09458927	7087388	NONE		09462517
6403374	NONE		09465142	6511815	NONE		09467628	7067324	US20010006820		09759629
NONE	US20030044789		09875620	NONE	US20020146741		09918589	6638713	US20030027238		09995961
NONE	US20020164674		10057505	6780975	US20030036178		10071976	NONE	US20030087328		10105735
NONE	US20030036106		10133528	NONE	US20030224469		10161482	NONE	US20030027236		10170170
NONE	US20030170767		10293580	NONE	US20040171107		10311030

Correspondence name and address
	FISH & RICHARDSON P.C., P.A.
	RONALD C. LUNDQUIST
	60 SOUTH SIXTH STREET, SUITE 3300
	MINNEAPOLIS, MN 55402

Assignment: 2

Reel/Frame:	037781/0332			Pages:	3
		Recorded:	02/11/2016
Conveyance:	ASSIGNEE CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2010

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Properties

Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #
7776905	US20070244159		11786001	7645789	US20090131492		11975297	8415387	US20100113555		12619412
8623905	US20110060024		12767472	8598181	US20100331344		12829879	8575209	US20110071206		12948162
NONE	US20110251253		13072380	8552034	US20110256220		13081750	8507687	US20110263654		13082156
NONE	US20130186801		13750069	8952049	US20130178471		13781392	8816093	US20130274477		13913876
8742122	US20130296379		13940361	8912199	US20140057906		14058839	NONE	US20140163068		14069571

Correspondence name and address
	FINNEGAN HENDERSON
	901 NEW YORK AVE., N.W.W
	WASHINGTON, DC 20001

Assignment: 3

Reel/Frame:	031556/0181			Pages:	14
		Recorded:	11/06/2013
Attorney Dkt #:	VPI/07-118 US CP1
Conveyance:	ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS).

Assignors

HADIDA-RUAH, SARA

Exec Dt:

12/12/2012

MILLER, MARK THOMAS

Exec Dt:

12/12/2012

BEAR, BRIAN RICHARD

Exec Dt:

12/12/2012

ZHOU, JINGLAN

Exec Dt:

12/12/2012

MCCARTNEY, JASON

Exec Dt:

12/13/2012

GROOTENHUIS, PETER DIEDERICK JAN

Exec Dt:

12/12/2012

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

12/14/2012

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

130 WAVERLY STREET

CAMBRIDGE, MASSACHUSETTS 02139

Properties

Pat #

Pub #

Intl #

App #

Pat #

Pub #

Intl #

App #

7754739

US20080286204

12117948

7754739

US20080286204

12117948

Correspondence name and address
	VERTEX PHARMACEUTICALS INCORPORATED
	130 WAVERLY STREET
	CAMBRIDGE, MA 02139

Assignment: 4

Reel/Frame:	031424/0361			Pages:	5
		Recorded:	10/17/2013
Attorney Dkt #:	PHAR-129 WO, US, CN1-CN3
Conveyance:	ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS).

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

10/17/2013

Assignee

VERTEX PHARMACEUTICALS (CANADA) INCORPORATED

1275 ARMAND-FRAPPIER BLVD

LAVAL, QUEBEC, CANADA H7V 4A7

Properties

Pat #

Pub #

Intl #

App #

Pat #

Pub #

Intl #

App #

Pat #

Pub #

Intl #

App #

6881741

US20040116509

10166031

7985769

US20060142347

11042442

8329924

US20110200553

13081780

NONE

US20130123242

13661508

Correspondence name and address
	VERTEX PHARMACEUTICALS INCORPORATED
	130 WAVERLY STREET
	CAMBRIDGE, MA 02139

Assignment: 5

Reel/Frame:	034660/0509			Pages:	4
		Recorded:	12/18/2014
Attorney Dkt #:	VPI/97-12 US CPA1
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/01/2014

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Properties

Pat #

Pub #

Intl #

App #

Pat #

Pub #

Intl #

App #

6436989

NONE

08998050

6436989

NONE

08998050

Correspondence name and address
	VERTEX PHARMACEUTICALS INCORPORATED
	50 NORTHERN AVENUE
	BOSTON, MA 02210

Assignment: 6

Reel/Frame:	033292/0311			Pages:	577
		Recorded:	07/10/2014
Attorney Dkt #:	MBL-1-B (380080-6)
Conveyance:	SECURITY INTEREST

Assignors

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

07/09/2014

VERTEX PHARMACEUTICALS (SAN DIEGO) LLC

Exec Dt:

07/09/2014

Assignee

MACQUARIE US TRADING LLC

125 WEST 55 STREET

NEW YORK, NEW YORK 10019

Properties

Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #
5665774	NONE		08027870	5585397	NONE		08142327	5620971	NONE		08217982
5552041	NONE		08317161	5744485	NONE		08377283	5543423	NONE		08377285
5723459	NONE		08377315	5783701	NONE		08393460	6127372	NONE		08424372
5693847	NONE		08424802	5691372	NONE		08424810	5723490	NONE		08424819
5861267	NONE		08432693	5726184	NONE		08444567	5856353	NONE		08477937
6372778	NONE		08484326	6037370	NONE		08486004	5978740	NONE		08512815
5883123	NONE		08540345	5763488	NONE		08550453	5646180	NONE		08567199
6008217	NONE		08575641	5883252	NONE		08592777	5717092	NONE		08626259
5807876	NONE		08636361	6128582	NONE		08640164	5912269	NONE		08640260
5985863	NONE		08712878	5945413	NONE		08724563	6153579	NONE		08731336
5811434	NONE		08748448	5780484	NONE		08749114	6124328	NONE		08795956
6344465	NONE		08801780	5880152	NONE		08814945	5945418	NONE		08822373
6054472	NONE		08832165	6147080	NONE		08862925	6093742	NONE		08884160
5935954	NONE		08961551	5990155	NONE		08977365	6057159	NONE		08989454
6436989	NONE		08998050	5945407	NONE		09015811	6162613	NONE		09025580
6268384	NONE		09085441	6056920	NONE		09092797	5977137	NONE		09115394
6004957	NONE		09121008	6183121	NONE		09128314	6201118	NONE		09136339
6117639	NONE		09144759	6172086	NONE		09198175	6177565	NONE		09235894
6303287	NONE		09257667	6201116	NONE		09277354	6265380	NONE		09293247
7438920	NONE		09303216	6608060	NONE		09336266	6225350	NONE		09393520
6392046	NONE		09409808	7065452	NONE		09431469	6387641	NONE		09457040
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6528276	NONE		09570267	6878728	NONE		09591464	6559137	NONE		09602494
6395763	NONE		09602703	6326387	NONE		09616539	6849716	NONE		09642749
6531474	NONE		09665503	6608067	NONE		09677382	7216041	NONE		09678016
6284778	NONE		09678265	6559304	NONE		09688301	6613743	US20020049201		09731129
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7098330	US20050004110		09952878	6495582	US20020177618		09953120	7115739	US20040097501		09953471
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6784195	US20020151574		09971497	6849267	US20030049820		09971533	6528509	US20030040536		09972437
7205327	US20020169177		10012722	6632809	US20030119868		10015332	6664247	US20030036543		10025164
6989385	US20030055068		10026967	6653300	US20030004161		10026975	7625913	US20040214814		10026992
6653301	US20030078275		10027001	6727251	US20030022885		10034019	6656939	US20030004164		10034683
6660748	US20020123507		10039886	6677359	US20020107240		10039896	6849630	US20030186960		10039898
6528533	US20020103190		10039900	6747042	US20020107241		10040931	7105546	US20030144253		10060662
6743791	US20030092714		10071699	6720335	US20030064977		10094763	6825224	US20020161038		10125617
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6762179	US20030119856		10154118	7078209	US20030119793		10166234	7517987	US20030232846		10166437
6632942	US20030176691		10168463	6949655	US20030191117		10170965	6552019	NONE		10171017
6689778	US20030171389		10171895	6825190	US20040009996		10172888	6909000	US20030119752		10193048
6608087	NONE		10198407	6875789	US20030139452		10212292	6750239	US20030144337		10212294
6916798	US20040024040		10212471	6593357	NONE		10225719	7109357	US20030119899		10229981
7335792	US20030162993		10268440	6649640	US20030195241		10272622	7241796	US20030134889		10280940
7087642	US20040029939		10287405	6716860	US20030109526		10307636	7358273	US20030232986		10314103
6800626	US20030149037		10327020	6699865	US20030225151		10335793	7820671	US20050197299		10344112
7659240	US20030171558		10345453	7041687	US20040009968		10350806	6967214	US20030195202		10351731
7186737	US20040044002		10365719	7410956	US20040019017		10366192	6838474	US20030207871		10370171
7091343	US20040009974		10389296	6846928	US20030225073		10389707	7179826	US20040002496		10389709
7494988	US20030236242		10391932	6930116	US20040024030		10395331	6759535	US20030203905		10400269
7273885	US20040018986		10412600	7960398	US20040048797		10419327	7304061	US20040029857		10424280
7271179	US20040038992		10430805	6994868	US20040048861		10437419	7414046	US20040043989		10444588
7122552	US20030236244		10449742	7727992	US20100105701		10459420	7388017	US20040266731		10607716
7553852	US20040072850		10609147	7442718	US20040127488		10613650	7615356	US20040110123		10620312
7205305	US20050009844		10622320	7008948	US20040224944		10624800	7354919	US20050090536		10626356
7491730	US20040039007		10632340	7531536	US20050038023		10632428	7115637	US20040132729		10638126
7304071	US20040106615		10639784	7074782	US20040053920		10645043	7169779	US20040142927		10658111
6949580	US20040082631		10686690	7056944	US20040102506		10688613	7390815	US20040116454		10692355
7262200	US20040167121		10694534	7312227	US20040147507		10700333	7259161	US20040097504		10700936
7348335	US20040176271		10702113	7279469	US20040214817		10715111	7943593	US20050059734		10728114
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7485664	US20040186088		10741164	7612091	US20040192612		10743563	7432292	US20040167187		10749121
7439249	US20040186116		10750326	7495014	US20040235886		10767638	7253187	US20040229875		10770814
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7077018	US20050235762		10833496	RE40245	NONE		10833995	7183307	US20040209935		10837848
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7531556	US20060019956		11115661	7354939	US20060106069		11128870	7358258	US20060058318		11129114
NONE	US20060128696		11130659	7531570	US20050267101		11140649	7820817	US20060019962		11140808
7452873	US20050222237		11145356	7569604	US20060074076		11165254	7495103	US20060074075		11165818
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7528142	US20070249031		11592119	8394803	US20130030004		11593418	7741321	US20080113985		11594431
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7527952	US20070124083		11645289	7691902	US20080044355		11647092	7767816	US20070203142		11654375
7915305	US20070219205		11656876	7598277	US20070142334		11671440	7659283	US20070213327		11705556
7622463	US20080167289		11706070	8003660	US20070213315		11709662	8039475	US20070212683		11711213
7964624	NONE		11711845	8039623	US20070161789		11716248	7872031	US20070254868		11726170
8741912	US20090088445		11732845	7490513	US20070204690		11747142	7553855	US20080090864		11748073
7488727	US20070249645		11763693	7442790	US20080015172		11770093	7902239	US20080014189		11774702
NONE	US20070270420		11776756	7776905	US20070244159		11786001	8669081	US20070190634		11786150
8841483	US20070238733		11786166	7589214	US20070298065		11786464	7763629	US20090062292		11786578
7829590	US20090286840		11786579	7598245	US20080096901		11787165	8058271	US20070270386		11801686
7659268	US20080019915		11804726	8486989	US20080045480		11805085	7851495	US20080070965		11805243
8853244	US20080045570		11805418	8883781	US20070287717		11811909	7834000	US20080004261		11818224
7858790	US20080033002		11823762	7671221	US20080009524		11824606	7842712	US20090048250		11841233
8829204	US20080071095		11841646	7696201	US20080176843		11893245	7786107	US20100063021		11894092
7705031	US20080306129		11933724	8163737	US20090176769		11955874	7645789	US20090131492		11975297
8691848	US20090048226		12009829	7906550	US20080125376		12026705	8314141	US20090143312		12031486
8809353	US20080167305		12050289	7951809	US20090203702		12062495	7834200	US20090048429		12074983
7666647	US20080262205		12079917	7745444	US20080311079		12082668	8304414	US20080287444		12109598
8993600	US20080306062		12114935	8969386	US20150031708		12117941	7754739	US20080286204		12117948
8193194	US20080293737		12124303	7960415	US20090093416		12140497	NONE	US20090246820		12147861
8022041	US20090012149		12165838	7846951	US20090018140		12183580	8188071	US20090124602		12187909
7994174	US20090105271		12212063	7919523	US20090042973		12217517	8268873	US20090030051		12221921
8263605	US20090227614		12224270	7777069	US20090093639		12228164	8252923	US20100137583		12231982
7875712	US20090215736		12235820	8188095	US20090176771		12246778	8519137	US20090099233		12249230
8389734	US20090118333		12249251	8779197	US20090118338		12249270	8173635	US20090291937		12262459
8426359	US20090291902		12265125	7994166	US20090131440		12269108	8097636	US20090124655		12269109
7919520	US20090176782		12269429	8507524	US20090143381		12271088	7884199	US20090191555		12272425
8188281	US20090176763		12273799	8163772	US20090099230		12283702	7973162	US20090099222		12287055
NONE	US20100028874		12298353	8507534	US20090170905		12327902	8124781	US20090176989		12327915
NONE	US20090176839		12327922	8217172	US20100063284		12329179	7872129	US20090118278		12338129
8101767	US20090227797		12351401	8324242	US20090298876		12351447	8101378	US20100248304		12355880
7842686	US20090186882		12356745	7906650	US20090131456		12359749	7829723	US20090170915		12365424
8455497	US20090274650		12370175	8299099	US20090221597		12392298	8129399	US20090181938		12410553
8227615	US20090246137		12410725	7915385	US20090264623		12416777	8563573	US20090253736		12422496
7888384	US20090253682		12424883	8399615	US20100063252		12430207	8372850	US20100022502		12433998
8163732	US20100081645		12434154	7777048	US20090221835		12435646	8268829	US20090221602		12436407
8268818	US20100144721		12438995	8481538	US20100144739		12441187	8129387	US20100099686		12448258
8247421	US20100189773		12448489	8129381	US20090281128		12464380	7838517	US20090281082		12466420
8192972	US20110014680		12471896	8076357	US20100069434		12471950	8178055	US20090238727		12475381
8034832	US20090325935		12478372	8853152	US20090247468		12481962	8067606	US20090325955		12483312
8206659	US20100314051		12483787	8426425	US20100022507		12486235	7846954	US20100004300		12495880
8575208	US20100272681		12528952	8759353	US20110059987		12528977	8236832	US20090306155		12538396
NONE	US20100081657		12540516	7982037	US20090312543		12545347	7919513	US20090318452		12550042
7989481	US20090326023		12550649	8653088	US20090325968		12552003	8193352	US20100063069		12552430
8153668	US20090324545		12555203	8153655	US20100087479		12556845	NONE	US20100137305		12562181
8071618	US20100137359		12562277	8426201	US20100081163		12568604	8716338	US20100087490		12568717
8022202	US20100190765		12569237	8468975	US20110087136		12577679	8455507	US20120095014		12595703
8268811	US20100317641		12598275	8383633	US20100215772		12598276	NONE	US20110046104		12598277
8258116	US20100172866		12598802	NONE	US20110060013		12601026	8513282	US20100113508		12605053
8314239	US20100113509		12605250	8436014	US20100130547		12605266	8415387	US20100113555		12619412
8217056	US20100234423		12620845	8399479	US20100168158		12623626	NONE	US20100105914		12630350
7956052	US20100087435		12630874	8642779	US20100087467		12634136	8354427	US20100184739		12635927
8536136	US20100330109		12639162	8841308	US20100222318		12642447	8367660	US20100168094		12643188
8337754	US20110151482		12644839	8524720	US20100256170		12651639	7883881	US20100227814		12652152
8637457	US20100174077		12661319	8569337	US20120136000		12670989	8461149	US20110263575		12673287
8492546	US20110009424		12675638	8039491	US20100105739		12683457	8343980	US20110021495		12688163
8242272	US20100184980		12695292	8236833	US20100130548		12697671	8372843	US20100137331		12698186
8524767	US20100249113		12704605	8273896	US20100234606		12704903	8397592	US20110203392		12709414
8802844	US20100249180		12711474	8017619	US20100280026		12713811	8153642	US20100160316		12714871
8501450	US20110244549		12718340	8188283	US20100261750		12722642	8236815	US20100184753		12724077
8476442	US20100267768		12728173	8481524	US20110136789		12751016	7998987	US20100190774		12756301
8314125	US20100204255		12761502	8426426	US20110104207		12761576	8623905	US20110060024		12767472
7973038	US20100210638		12768894	7989456	US20100222367		12774376	8163917	US20100311743		12775885
8012999	US20100227888		12782967	8258148	US20100311720		12785676	8269012	US20110124684		12788608
8269013	US20100305155		12788715	8263776	US20100305156		12788723	8664219	US20110020376		12791976
8410133	US20110021559		12792044	8518953	US20110020377		12792050	8367691	US20100311746		12794202
8067417	US20110021519		12796174	8637511	US20100310675		12796297	8344153	US20100316605		12796825
NONE	US20110112114		12797250	8383858	US20100298568		12806014	8552006	US20110008259		12813876
8937064	US20110118255		12817785	8372746	US20110128668		12824670	8217048	US20110104115		12825237
8598181	US20100331344		12829879	8362032	US20110059965		12830743	8163720	US20110082117		12844047
8372835	US20110081364		12847136	NONE	US20110053916		12855263	8324220	US20110003814		12877793
NONE	US20110224197		12878246	8129546	US20110077269		12879237	8404865	US20110065928		12884925
8188134	US20110178146		12891973	8557833	US20110020469		12894465	8293929	US20110071298		12902811
8399458	US20120028965		12903390	8344147	US20110124869		12909750	8389727	US20110123449		12909789
8232302	US20110144123		12913089	8143297	US20110098328		12913869	8236829	US20110112156		12938556
8329702	US20110059984		12941435	8039661	US20110190507		12942287	8232406	US20110059936		12942395
8318467	US20110129896		12944909	8575209	US20110071206		12948162	8211935	US20110178061		12971609
8168798	US20110137037		12971649	NONE	US20110086006		12972175	8278297	US20120028966		12977197
8252787	US20120010197		12977222	8378124	US20110213161		12982209	9067932	US20120071494		13014505
8252541	US20110117112		13018908	8377926	US20110183966		13020947	8093392	US20110130436		13022820
8399478	US20110288095		13033872	8541025	US20110236478		13034039	8440706	US20110165120		13036930
8471029	US20110230519		13053172	8324207	US20110172229		13069889	NONE	US20110251253		13072380
8372873	US20110182856		13074772	8552034	US20110256220		13081750	8507687	US20110263654		13082156
8518938	US20120165333		13090563	NONE	US20110257223		13092838	8633210	US20120071657		13094183
8343998	US20110207774		13099643	8598164	US20110306607		13102335	8410112	US20120040020		13104291
8969356	US20120178756		13106167	8962631	US20120035407		13106173	9096584	US20120177748		13106178
9334244	US20120122884		13106184	9062008	US20120035408		13106337	9630956	US20120027874		13106476
8338412	US20110281878		13107802	8318733	US20110312958		13108077	8541453	US20110306637		13112115
8404849	US20110288121		13112868	8263777	US20110294849		13114215	8664273	US20120045415		13153199
8563593	US20120015999		13155420	8623869	US20120046295		13167654	8304423	US20120196857		13171652
8431605	US20120004216		13174844	8586615	US20120010257		13178677	NONE	US20120014912		13182695
8679740	US20120129155		13186985	8967024	US20130019725		13187416	8445681	US20120165367		13193739
8288400	US20120183577		13205291	8394952	US20120149898		13206638	NONE	US20110301195		13206954
8329662	US20110301096		13210712	8524906	US20120039849		13211502	NONE	US20120046330		13214419
8686157	US20120157684		13216530	8268999	US20120053187		13216606	NONE	US20120064157		13219590
8481578	US20120165378		13234332	8404852	US20120010222		13234634	8614325	US20120071504		13237303
8618152	US20120014914		13238386	8524902	US20120277425		13253196	8278306	US20120065213		13253322
8367697	US20120149680		13275551	8686143	US20120157429		13280670	NONE	US20120172379		13289300
8541445	US20120178778		13289320	8501426	US20120058502		13294635	9137973	US20120184524		13308609
8563576	US20120184534		13308612	8288537	US20120077830		13309117	NONE	US20120129212		13322006
8338597	US20120190699		13325089	8598361	US20120232275		13347926	8481551	US20120184512		13349789
8481552	US20120184741		13349845	8466288	US20120202784		13349868	8471014	US20120184742		13349884
8476281	US20120184564		13349984	8592602	US20120190856		13351573	8557818	US20120122879		13356924
8410274	US20120214841		13358778	8916565	US20120196869		13364586	10385070	US20120245136		13398184
8343763	US20120149742		13402519	NONE	US20120316186		13403169	8450489	US20120165307		13409702
8362253	US20120165372		13413327	8461352	US20120259129		13416157	8828996	US20120264749		13418737
NONE	US20120258983		13418927	8309587	US20120178713		13419936	8637666	US20120178926		13424736
8598205	US20120208841		13439379	8877759	US20130095193		13440981	8501446	US20120258958		13441287
8741931	US20120214799		13442244	8398941	US20120201727		13450303	8461342	US20120203006		13450805
8674108	US20130281487		13452758	8410132	US20130018070		13453193	8883766	US20120208790		13457855
8653103	US20120277268		13467185	NONE	US20120232059		13475388	8530489	US20120309963		13477663
8309543	US20120238578		13478538	8712749	US20130137125		13479720	8353969	US20120241100		13480747
8802700	US20120309758		13492164	8592577	US20120271045		13497139	9125922	US20130157979		13527832
8822469	US20130018035		13531461	9096602	US20130017273		13531464	9309250	US20130034616		13531467
8524910	US20120270869		13533326	8357702	US20120308606		13537903	8546414	US20120270318		13538667
8865751	US20130090479		13540651	8529882	US20120282219		13541436	8513414	US20130102782		13541504
8609703	US20130011923		13544312	8497295	US20120283243		13546185	8663936	US20120283314		13558124
NONE	US20130053395		13560119	8895740	US20130053388		13560122	8809335	US20130053394		13560131
8785444	US20130116228		13564838	8779127	US20130066069		13585861	8461345	US20120316345		13591380
8618106	US20120322793		13593674	8461156	US20120322798		13595225	NONE	US20130072440		13608079
NONE	US20130018071		13622598	NONE	US20130281445		13623962	NONE	US20130261114		13623970
8802868	US20130143918		13624241	8779156	US20130090351		13625135	NONE	US20130102629		13625137
NONE	US20130085150		13625151	NONE	US20130090364		13625160	8796312	US20130023538		13627222
8697698	US20130096128		13631488	8853217	US20130096139		13631727	8765751	US20130089624		13631730
8846686	US20130089625		13631732	9035053	US20130184292		13631759	NONE	US20130089626		13633114
8586589	US20130035310		13633478	9035072	US20130324743		13642642	NONE	US20130085158		13646007
8629162	US20130035327		13647034	NONE	US20130096302		13650586	8604203	US20130040986		13652056
8853254	US20130184276		13652655	NONE	US20130158071		13657299	NONE	US20130338188		13657321
NONE	US20130131107		13657345	NONE	US20130184258		13661337	8835639	US20130072522		13669735
9254291	US20130116238		13672538	8841449	US20130115310		13672937	8846917	US20130115311		13672944
8841337	US20130115312		13672949	8841450	US20130115313		13672954	8846918	US20130115314		13672958
8754222	US20130072687		13678840	NONE	US20130184259		13679012	8536195	US20130084639		13679028
NONE	US20130331412		13681110	8785476	US20130079367		13682075	8614327	NONE		13690924
NONE	US20130096277		13692565	8679406	US20130095500		13693492	NONE	US20130157258		13704107
9156880	US20130331310		13709610	8623894	US20130109717		13714911	8633189	US20130196983		13718539
8871812	US20130101554		13718608	NONE	US20130190289		13723668	NONE	US20130203706		13724014
NONE	US20130131356		13735757	NONE	US20140187781		13736988	8815866	US20130137703		13737173
NONE	US20130131359		13740707	NONE	US20140113005		13742948	8492403	US20130131109		13745919
8865771	US20130231370		13747716	NONE	US20130186801		13750069	8710075	US20130231364		13750400
8741922	US20130137722		13751656	NONE	US20130195797		13754365	NONE	US20130267498		13765864
NONE	US20140065103		13767347	8871904	US20130172276		13767577	8759389	NONE		13768119
8978491	US20130160572		13776537	9038488	US20130160573		13776563	8763559	US20130176035		13777239
8748612	US20130178496		13778949	NONE	US20130224293		13779654	NONE	US20130177531		13780373
8952049	US20130178471		13781392	8735593	US20130245273		13785019	8754224	US20130317060		13785692
NONE	US20130261077		13787418	8846896	US20130253181		13793900	8916538	US20140154210		13794380
NONE	US20140256703		13798875	NONE	US20130273003		13800148	8895723	US20130281687		13845415
NONE	US20130324725		13845934	8741939	US20130252333		13848970	NONE	US20140303137		13857253
NONE	US20140044802		13857658	NONE	US20140113933		13858750	NONE	US20130274180		13861791
NONE	US20130310418		13868123	9296701	US20130281431		13868703	8822681	US20130237516		13870173
NONE	US20140018352		13871174	NONE	US20130245010		13871349	8741933	US20130237568		13871356
9216969	US20130237569		13871364	9193722	US20130252939		13873591	NONE	US20140308242		13879736
NONE	US20130245011		13887839	9676759	US20140038936		13888960	8912326	US20130261305		13903506
NONE	US20140010784		13904109	8722889	US20130345197		13908267	8765957	US20140012003		13908349
9040542	US20130267540		13908483	8969359	US20130289002		13908593	NONE	US20140050697		13911410
NONE	US20130317222		13911483	8816093	US20130274477		13913876	8871774	US20140005192		13918048
NONE	US20140005197		13918110	NONE	US20130345218		13918115	NONE	US20130281476		13919369
8846753	US20130296306		13928719	NONE	US20140141099		13930052	NONE	US20130344476		13932792
NONE	US20150008896		13933233	8722704	US20130296364		13936277	NONE	US20130303484		13938768
8742122	US20130296379		13940361	8796453	US20130303764		13940421	9572809	US20140045791		13942342
9012496	US20140088160		13942617	8785640	US20130303570		13944171	9018216	US20140031318		13945257
8889875	US20130317020		13957678	8962642	US20140045812		13961218	8841282	US20130338119		13967732
NONE	US20140187770		13968274	9550761	US20140080825		13972151	9051324	US20140073653		14018983
NONE	US20140094499		14027791	9029546	US20140148434		14030153	9102672	US20140024672		14031349
NONE	US20140023706		14031360	8952050	US20140080826		14036286	NONE	US20140107049		14042817
8999632	US20140134596		14045373	8912198	US20140107093		14053737	8962856	US20140121381		14055247
NONE	US20140336219		14055830	9376448	US20140045869		14056560	8912199	US20140057906		14058839
9321725	US20140121379		14061004	8741925	NONE		14063785	9422271	US20140249137		14068606
NONE	US20140163068		14069571	NONE	US20140056847		14069638	8969382	US20140228399		14074158
8853415	US20140072995		14079664	NONE	US20140155626		14082525	9073875	US20140179699		14083693
8796308	US20140228400		14084203	NONE	US20140171427		14089031	9663519	US20140275130		14098602
9340546	US20140163000		14098606	8957078	US20140275009		14098640	8969360	US20140275021		14098655
NONE	US20150158868		14098667	8829007	US20140142119		14098867	9051319	US20140094473		14099054
8999976	US20140235625		14100748	NONE	US20140187774		14100952	NONE	US20140171454		14101543
NONE	US20140288347		14105778	NONE	US20150150879		14107700	NONE	US20140107318		14109631
9598454	US20140243283		14132662	NONE	US20140163011		14135065	NONE	US20140155431		14135204
NONE	US20140112988		14135323	NONE	US20140187772		14139889	NONE	US20140194444		14155624
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Reel/Frame:	035077/0479			Pages:	5
		Recorded:	03/03/2015
Attorney Dkt #:	VTEX.010C1
Conveyance:	ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS).

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

02/18/2015

Assignee

ALIOS BIOPHARMA, INC.

260 E. GRAND AVENUE

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SOUTH SAN FRANCISCO, CALIFORNIA 94080

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VERTEX PHARMACEUTICALS INCORPORATED

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ALIOS BIOPHARMA, INC.

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VERTEX PHARMACEUTICALS INCORPORATED

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ALIOS BIOPHARMA, INC.

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VERTEX PHARMACEUTICALS INCORPORATED

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VERTEX PHARMACEUTICALS INCORPORATED

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VERTEX PHARMACEUTICALS INCORPORATED

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VERTEX PHARMACEUTICALS INCORPORATED

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VERTEX PHARMACEUTICALS INCORPORATED

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VERTEX PHARMACEUTICALS INCORPORATED

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VERTEX PHARMACEUTICALS INCORPORATED

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VERTEX PHARMACEUTICALS INCORPORATED

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VERTEX PHARMACEUTICALS INCORPORATED

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VERTEX PHARMACEUTICALS INCORPORATED

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VERTEX PHARMACEUTICALS INCORPORATED

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VERTEX PHARMACEUTICALS INCORPORATED

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VERTEX PHARMACEUTICALS INCORPORATED

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VERTEX PHARMACEUTICALS INCORPORATED

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VERTEX PHARMACEUTICALS INCORPORATED

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VERTEX PHARMACEUTICALS INCORPORATED

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Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Properties

Pat #

Pub #

Intl #

App #

Pat #

Pub #

Intl #

App #

Pat #

Pub #

Intl #

App #

10022352

US20160271105

15078800

9974781

15234877

15659926

15949404

Correspondence name and address
	CHRISTINA M. RODRIGO, PH.D.
	FINNEGAN
	901 NEW YORK AVENUE NW
	WASHINGTON, DC 20001

Assignment: 32

Reel/Frame:	046412/0215			Pages:	2
		Recorded:	06/22/2018
Attorney Dkt #:	10275.0050-13000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

10662192

US20190144450

16006105

Correspondence name and address
	ERIC LEE
	FINNEGAN
	901 NEW YORK AVENUE NW
	WASHINGTON, DC 20001

Assignment: 33

Reel/Frame:	047245/0882			Pages:	2
		Recorded:	06/26/2018
Attorney Dkt #:	10275.0046-06 AND 22-06
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02110

Properties

Pat #

Pub #

Intl #

App #

Pat #

Pub #

Intl #

App #

15807663

15900147

Correspondence name and address
	ERIC LEE
	FINNEGAN
	901 NEW YORK AVENUE NW
	WASHINGTON, DC 20001

Assignment: 34

Reel/Frame:	049265/0817			Pages:	2
		Recorded:	05/23/2019
Attorney Dkt #:	10275.0032-04000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

10906891

US20190270728

16109931

Correspondence name and address
	LESLIE MCDONELL
	FINNEGAN
	901 NEW YORK AVENUE NW
	WASHINGTON, DC 20001

Assignment: 35

Reel/Frame:	049427/0443			Pages:	2
		Recorded:	06/11/2019
Attorney Dkt #:	10275.0061-05000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

11147770

US20190274959

16299675

Correspondence name and address
	ERIC LEE
	50 NORTHERN AVENUE
	BOSTON, MA 02210

Assignment: 36

Reel/Frame:	049748/0211			Pages:	2
		Recorded:	07/15/2019
Attorney Dkt #:	10275.0021-19000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

10626111

US20190322650

16197732

Correspondence name and address
	FINNEGAN, HENDERSON, FARABOW, GARRETT & DUNNER LLP
	901 NEW YORK AVENUE NW
	ATTN: IP DEPARTMENT
	WASHINGTON, DC 20001-4413

Assignment: 37

Reel/Frame:	049757/0853			Pages:	2
		Recorded:	07/15/2019
Attorney Dkt #:	10275.0034-03000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

NONE

US20190210991

16059724

Correspondence name and address
	LESLIE MCDONELL
	FINNEGAN
	901 NEW YORK AVENUE NW
	WASHINGTON, DC 20001

Assignment: 38

Reel/Frame:	051596/0922			Pages:	2
		Recorded:	01/15/2020
Attorney Dkt #:	10275.0031-17000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

10975061

US20200115366

16276887

Correspondence name and address
	ANTOINETTE E. NIBBS
	FINNEGAN
	901 NEW YORK AVENUE NW
	WASHINGTON, DC 20001

Assignment: 39

Reel/Frame:	051841/0330			Pages:	2
		Recorded:	02/07/2020
Attorney Dkt #:	10275.0026-02000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

NONE

US20200338063

16722290

Correspondence name and address
	FINNEGAN, HENDERSON, FARABOW, GARRETT & DUNNER LLP
	901 NEW YORK AVENUE NW
	WASHINGTON, DC 20001-4413

Assignment: 40

Reel/Frame:	051841/0437			Pages:	2
		Recorded:	02/07/2020
Attorney Dkt #:	10275.0022-07000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

NONE

US20200377484

16783338

Correspondence name and address
	FINNEGAN, HENDERSON, FARABOW, GARRETT & DUNNER LLP
	901 NEW YORK AVENUE NW
	WASHINGTON, DC 20001-4413

Assignment: 41

Reel/Frame:	051929/0224			Pages:	2
		Recorded:	02/13/2020
Attorney Dkt #:	10275.0021-20000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

11084804

US20210024505

16789945

Correspondence name and address
	FINNEGAN, HENDERSON, FARABOW, GARRETT & DUNNER LLP
	901 NEW YORK AVENUE NW
	WASHINGTON, DC 20001-4413

Assignment: 42

Reel/Frame:	052614/0625			Pages:	2
		Recorded:	05/08/2020
Attorney Dkt #:	10275.0046-07000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

11291662

US20210251978

16704713

Correspondence name and address
	FINNEGAN, HENDERSON, FARABOW, GARRETT & DUNNER LLP
	901 NEW YORK AVENUE NW
	ATTN: IP DEPARTMENT
	WASHINGTON, DC 20001-4413

Assignment: 43

Reel/Frame:	052614/0668			Pages:	2
		Recorded:	05/08/2020
Attorney Dkt #:	10275.0054-03000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

11564916

US20210023070

16842480

Correspondence name and address
	FINNEGAN, HENDERSON, FARABOW, GARRETT & DUNNER LLP
	901 NEW YORK AVENUE NW
	ATTN: IP DEPARTMENT
	WASHINGTON, DC 20001-4413

Assignment: 44

Reel/Frame:	053420/0587			Pages:	2
		Recorded:	08/06/2020
Attorney Dkt #:	10275.0024-05000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

11052075

US20200197380

16530240

Correspondence name and address
	FINNEGAN, HENDERSON, FARABOW, GARRETT & DUNNER LLP
	901 NEW YORK AVENUE NW
	ATTN: IP DEPARTMENT
	WASHINGTON, DC 20001-4413

Assignment: 45

Reel/Frame:	053420/0731			Pages:	2
		Recorded:	08/06/2020
Attorney Dkt #:	10275.0025-03000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

NONE

US20200085750

16523493

Correspondence name and address
	FINNEGAN, HENDERSON, FARABOW, GARRETT & DUNNER LLP
	901 NEW YORK AVENUE NW
	ATTN: IP DEPARTMENT
	WASHINGTON, DC 20001-4413

Assignment: 46

Reel/Frame:	053495/0941			Pages:	2
		Recorded:	08/14/2020
Attorney Dkt #:	1065272.000565
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

RE48266

NONE

16363905

Correspondence name and address
	BRYAN CAVE LEIGHTON PAISNER LLP
	1290 AVENUE OF THE AMERICAS
	NEW YORK, NY 10104

Assignment: 47

Reel/Frame:	055486/0097			Pages:	2
		Recorded:	03/03/2021
Attorney Dkt #:	10275.0025-04000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

NONE

US20220354797

17174764

Correspondence name and address
	FINNEGAN, HENDERSON, FARABOW, GARRETT & DUNNER LLP
	901 NEW YORK AVENUE NW
	ATTN: IP DEPARTMENT
	WASHINGTON, DC 20001-4413

Assignment: 48

Reel/Frame:	056409/0197			Pages:	2
		Recorded:	05/27/2021
Attorney Dkt #:	10275.0034-04000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

NONE

US20210238158

17003051

Correspondence name and address
	FINNEGAN, HENDERSON, FARABOW, GARRETT & DUNNER, LL
	901 NEW YORK AVENUE, NW
	WASHINGTON, DC 20001

Assignment: 49

Reel/Frame:	061101/0942			Pages:	2
		Recorded:	08/08/2022
Attorney Dkt #:	10275.0061-06000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

11752106

US20220241206

17475622

Correspondence name and address
	ERIC LEE
	FINNEGAN
	901 NEW YORK AVENUE NW
	WASHINGTON, DC 20001

Assignment: 50

Reel/Frame:	061118/0798			Pages:	2
		Recorded:	08/09/2022
Attorney Dkt #:	10275.0032-05000
Conveyance:	CHANGE OF ADDRESSS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

11578062

US20210340128

17104903

Correspondence name and address
	ANTOINETTE E. NIBBS
	FINNEGAN
	901 NEW YORK AVENUE NW
	WASHINGTON, DC 20001

Assignment: 51

Reel/Frame:	061987/0348			Pages:	2
		Recorded:	11/22/2022
Attorney Dkt #:	10275.0031-18000
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

11639347

US20220411410

17181931

Correspondence name and address
	ANTOINETTE E. NIBBS
	FINNEGAN
	901 NEW YORK AVENUE NW
	WASHINGTON, DC 20001

Assignment: 52

Reel/Frame:	062401/0173			Pages:	2
		Recorded:	01/17/2023
Attorney Dkt #:	1065272.000565CON
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

RE49500

NONE

17071566

Correspondence name and address
	BRYAN CAVE LEIGHTON PAISNER LLP
	1290 AVENUE OF THE AMERICAS
	NEW YORK, NY 10104

Assignment: 53

Reel/Frame:	063662/0496			Pages:	2
		Recorded:	05/16/2023
Attorney Dkt #:	1065272.000565 RE4
Conveyance:	CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

NONE

US20230183276

18173004

Correspondence name and address
	BRYAN CAVE LEIGHTON PAISNER LLP
	1290 AVENUE OF THE AMERICAS
	NEW YORK, NY 10104

Assignment: 54

Reel/Frame:	063783/0097			Pages:	2
		Recorded:	05/25/2023
Attorney Dkt #:	10275.0046-09000
Conveyance:	ASSIGNEE CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

NONE

US20230263794

17953412

Correspondence name and address
	FINNEGAN HENDERSON FARABOW GARRETT & DUNNER, LLP
	901 NEW YORK AVENUE, NW
	WASHINGTON, DC 20001

Assignment: 55

Reel/Frame:	063941/0993			Pages:	2
		Recorded:	06/09/2023
Attorney Dkt #:	10275.0026-03000
Conveyance:	ASSIGNEE CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

NONE

US20230364073

18091472

Correspondence name and address
	FINNEGAN HENDERSON FARABOW GARRETT & DUNNER, LLP
	901 NEW YORK AVENUE, NW
	WASHINGTON, DC 20001

Assignment: 56

Reel/Frame:	063955/0247			Pages:	2
		Recorded:	06/09/2023
Attorney Dkt #:	10275.0054-04000
Conveyance:	ASSIGNEE CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

NONE

US20230210839

18091476

Correspondence name and address
	FINNEGAN HENDERSON FARABOW GARRETT & DUNNER, LLP
	901 NEW YORK AVENUE, NW
	WASHINGTON, DC 20001

Assignment: 57

Reel/Frame:	064935/0708			Pages:	2
		Recorded:	09/18/2023
Attorney Dkt #:	10275.0024-06000
Conveyance:	ASSIGNEE CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

NONE

US20220031679

17333478

Correspondence name and address
	FINNEGAN HENDERSON FARABOW GARRETT & DUNNER, LLP
	901 NEW YORK AVENUE, NW
	WASHINGTON, DC 20001

Assignment: 58

Reel/Frame:	066196/0096			Pages:	2
		Recorded:	01/04/2024
Attorney Dkt #:	10275.0032-06000
Conveyance:	ASSIGNEE CHANGE OF ADDRESS

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

01/26/2016

Assignee

VERTEX PHARMACEUTICALS INCORPORATED

50 NORTHERN AVENUE

BOSTON, MASSACHUSETTS 02210

Property

Pat #

Pub #

Intl #

App #

NONE

US20230331712

17992294

Correspondence name and address
	FINNEGAN HENDERSON FARABOW GARRETT & DUNNER, LLP
	901 NEW YORK AVENUE, NW
	WASHINGTON, DC 20001

Assignment: 59

Reel/Frame:	039076/0224			Pages:	9
		Recorded:	07/05/2016
Attorney Dkt #:	ABX
Conveyance:	ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS).

Assignor

VERTEX PHARMACEUTICALS INCORPORATED

Exec Dt:

05/09/2016

Assignee

SPERO TRINEM, INC.

675 MASSACHUSETTS AVE.

14TH FLOOR

CAMBRIDGE, MASSACHUSETTS 02139

Properties

Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #
8481551	US20120184512		13349789	8481552	US20120184741		13349845	8471014	US20120184742		13349884
8476281	US20120184564		13349984	9125922	US20130157979		13527832	8912326	US20130261305		13903506
9040542	US20130267540		13908483	8969359	US20130289002		13908593	9572809	US20140045791		13942342
9018216	US20140031318		13945257