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Assignor Name : VYNE THERAPEUTICS INC.

Total Assignments: 6

Assignment: 1

Reel/Frame:	055326/0009			Pages:	15
		Recorded:	02/17/2021
Attorney Dkt #:	72295/ 0000044
Conveyance:	PATENT SECURITY AGREEMENT

Assignor

VYNE THERAPEUTICS INC.

Exec Dt:

02/17/2021

Assignee

PERCEPTIVE CREDIT HOLDINGS II, LP

51 ASTOR PLACE

10TH FLOOR

NEW YORK, NEW YORK 10003

Properties

Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #
7575739	US20040265240		10835359	7820145	US20050031547		10835505	7700076	US20100040561		10922358
9668972	US20050232869		11078902	8486376	US20050244342		11099942	8840869	US20050271598		11116761
7645803	US20060275221		11430437	7704518	US20060275218		11430599	9211259	US20060269485		11448490
8119150	US20070020304		11481596	10117812	US20070020213		11488989	8114385	US20070280891		11645444
8119109	US20070253911		11717897	9265725	US20080044444		11825406	8795693	US20080206159		11947751
8486374	US20080299220		12014088	8636982	US20090041680		12187840	8617100	US20090068118		12204771
9320705	US20120237453		12350650	9622947	US20090180970		12350854	8119106	US20090317338		12499609
9439857	US20110045037		12745417	8435498	US20100284938		12752718	8362091	US20100266510		12767511
8795635	US20100221195		12778591	8343945	US20100310476		12795164	8900553	US20110212033		12795213
8709385	US20110008266		12836444	8518378	US20110002857		12881856	8618081	US20110281827		13100724
8518376	US20110268665		13123213	9167813	US20120213709		13359709	9072667	US20120213710		13359787
8900554	US20120148503		13400330	8486375	US20120195836		13400337	8871184	US20130028850		13499475
8945516	US20130064777		13499501	10029013	US20130011342		13499709	9161916	US20130189191		13732024
8741265	US20130183251		13784085	8722021	US20130183250		13786902	8703105	US20130195769		13793617
9636405	US20130189193		13793893	8978936	US20130161351		13809669	9849142	US20130225536		13831396
9795564	US20140050673		13967546	9101662	US20150017103		14045528	10265404	US20140066524		14078746
9662298	US20140271494		14161134	9539208	US20140193502		14172466	9682021	US20140248219		14189559
9050253	US20140219929		14246533	9492412	US20140227199		14258700	9713643	US20140241998		14272551
8865139	US20140328770		14327040	8992896	US20150056149		14469792	9549898	US20150118164		14504942
9675700	US20150190409		14595882	9463919	US20150239645		14634208	10350166	US20150374625		14733418
10238746	US20160101184		14850655	9572775	US20160101051		14857282	10092588	US20170216334		15401743
10369102	US20180000734		15493807	10213512	US20170340743		15591733	9884017	US20170360705		15639114
10398641	US20180064638		15699692	10517882	US20180147218		15816850	10213384	US20180153804		15883134
10821077	US20190247310		15903275	10086080	US20180193468		15913574	10137200	US20180193469		15915386
11433025	US20190091149		15999088	10967063	US20190000980		16019623	NONE	US20190282501		16072046
11219631	US20190054106		16108799	10322085	US20190076356		16189767	10322186	US20190134203		16235964
10946101	US20190134204		16235986	10363216	US20190201339		16236704	10821187	US20190231886		16280921
NONE	US20190307778		16353911	NONE	US20190240239		16384589	10835613	US20190275157		16387381
10463742	US20190262456		16387407	NONE	US20200022912		16425610	10588858	US20200016077		16443649
11103454	US20200038324		16445000	10849847	US20200016068		16508611	10610599	US20200016271		16578252
NONE	US20230123488		16624244	NONE	US20200171057		16668491	NONE	US20200222320		16779884
NONE	US20200261586		16805201	NONE	US20210000842		16948352	NONE	US20210015927		16948631
NONE	US20210077509		17025156	NONE	US20210015928		17037070	NONE	US20210069335		17061018
NONE	US20210023226		17066752	11033491	US20210038517		17072243	11324691	US20210205212		17075217

Correspondence name and address
	MORRISON & FOERSTER LLP
	425 MARKET ST.
	SAN FRANCISCO, AR 94105

Assignment: 2

Reel/Frame:	058463/0208			Pages:	7
		Recorded:	12/22/2021
Attorney Dkt #:	13949.0999-00000
Conveyance:	ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS).

Assignor

VYNE THERAPEUTICS INC.

Exec Dt:

11/04/2021

Assignee

VYNE PHARMACEUTICALS INC.

520 U.S. HIGHWAY 22

SUITE 204

BRIDGEWATER, NEW JERSEY 08807

Properties

Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #
8618081	US20110281827		13100724	8871184	US20130028850		13499475	8945516	US20130064777		13499501
9849142	US20130225536		13831396	10265404	US20140066524		14078746	8865139	US20140328770		14327040
8992896	US20150056149		14469792	9675700	US20150190409		14595882	10238746	US20160101184		14850655
10213512	US20170340743		15591733	10398641	US20180064638		15699692	10517882	US20180147218		15816850
10086080	US20180193468		15913574	10137200	US20180193469		15915386	10322186	US20190134203		16235964
10946101	US20190134204		16235986	10821187	US20190231886		16280921	NONE	US20190240239		16384589
10835613	US20190275157		16387381	10463742	US20190262456		16387407	10849847	US20200016068		16508611
10610599	US20200016271		16578252	NONE	US20200171057		16668491	NONE	US20200261586		16805201
NONE	US20210015927		16948631	NONE	US20210077509		17025156	NONE	US20210015928		17037070
NONE	US20210069335		17061018	11324691	US20210205212		17075217

Correspondence name and address
	FINNEGAN, HENDERSON, FARABOW, GARRETT & DUNNER LLP
	901 NEW YORK AVENUE, NW
	WASHINGTON, DC 20001-4413

Assignment: 3

Reel/Frame:	061298/0194			Pages:	6
		Recorded:	10/04/2022
Attorney Dkt #:	15986.0070-13000
Conveyance:	ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS).

Assignor

VYNE THERAPEUTICS INC.

Exec Dt:

11/04/2021

Assignee

VYNE PHARMACEUTICALS INC.

520 U.S. HIGHWAY 22

SUITE 204

BRIDGEWATER, NEW JERSEY 08807

Property

Pat #

Pub #

Intl #

App #

NONE

US20230270760

17936562

Correspondence name and address
	FINNEGAN, HENDERSON, FARABOW, GARRETT & DUNNER LLP
	901 NEW YORK AVENUE NW
	WASHINGTON, DC 20001

Assignment: 4

Reel/Frame:	058463/0167			Pages:	6
		Recorded:	12/22/2021
Attorney Dkt #:	13949.0999-00000
Conveyance:	ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS).

Assignor

VYNE THERAPEUTICS INC.

Exec Dt:

12/09/2021

Assignee

VYNE PHARMACEUTICALS INC.

520 U.S. HIGHWAY 22

SUITE 204

BRIDGEWATER, NEW JERSEY 08807

Properties

Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #
8343945	US20100310476		12795164	8900553	US20110212033		12795213	8518376	US20110268665		13123213
10029013	US20130011342		13499709	9161916	US20130189191		13732024	9795564	US20140050673		13967546
9549898	US20150118164		14504942	10092588	US20170216334		15401743	9884017	US20170360705		15639114
10213384	US20180153804		15883134	11433025	US20190091149		15999088	10967063	US20190000980		16019623
11219631	US20190054106		16108799	10363216	US20190201339		16236704	NONE	US20190307778		16353911
10588858	US20200016077		16443649	NONE	US20230123488		16624244	NONE	US20200222320		16779884
NONE	US20210023226		17066752

Correspondence name and address
	FINNEGAN, HENDERSON, FARABOW, GARRETT & DUNNER LLP
	901 NEW YORK AVENUE, NW
	WASHINGTON, DC 20001-4413

Assignment: 5

Reel/Frame:	058925/0568			Pages:	24
		Recorded:	02/01/2022
Attorney Dkt #:	15986.0999-00000
Conveyance:	ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS).

Assignors

VYNE THERAPEUTICS INC.

Exec Dt:

01/12/2022

VYNE PHARMACEUTICALS INC.

Exec Dt:

01/12/2022

Assignee

JOURNEY MEDICAL CORPORATION

9237 EAST VIA DE VENTURA

SUITE 105

SCOTTSDALE, ARIZONA 85258

Properties

Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #	Pat #	Pub #	Intl #	App #
8343945	US20100310476		12795164	8900553	US20110212033		12795213	8618081	US20110281827		13100724
8518376	US20110268665		13123213	8871184	US20130028850		13499475	8945516	US20130064777		13499501
10029013	US20130011342		13499709	9161916	US20130189191		13732024	9849142	US20130225536		13831396
9795564	US20140050673		13967546	10265404	US20140066524		14078746	8865139	US20140328770		14327040
8992896	US20150056149		14469792	9549898	US20150118164		14504942	9675700	US20150190409		14595882
10238746	US20160101184		14850655	10092588	US20170216334		15401743	10213512	US20170340743		15591733
9884017	US20170360705		15639114	10398641	US20180064638		15699692	10517882	US20180147218		15816850
10213384	US20180153804		15883134	10086080	US20180193468		15913574	10137200	US20180193469		15915386
11433025	US20190091149		15999088	10967063	US20190000980		16019623	11219631	US20190054106		16108799
10322186	US20190134203		16235964	10946101	US20190134204		16235986	10363216	US20190201339		16236704
10821187	US20190231886		16280921	NONE	US20190240239		16384589	10835613	US20190275157		16387381
10463742	US20190262456		16387407	10588858	US20200016077		16443649	10849847	US20200016068		16508611
10610599	US20200016271		16578252	NONE	US20230123488		16624244	NONE	US20200171057		16668491
NONE	US20200222320		16779884	NONE	US20200261586		16805201	NONE	US20210015927		16948631
NONE	US20210077509		17025156	NONE	US20210015928		17037070	NONE	US20210069335		17061018
NONE	US20210023226		17066752	11324691	US20210205212		17075217	NONE	US20230346805		17597892

Correspondence name and address
	FINNEGAN, HENDERSON, FARABOW, GARRETT & DUNNER LLP
	901 NEW YORK AVENUE, NW
	WASHINGTON, DC 20001-4413

Assignment: 6

Reel/Frame:	061596/0333			Pages:	23
		Recorded:	10/04/2022
Attorney Dkt #:	15986.0070-13000
Conveyance:	ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS).