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Reel/Frame:	043267/0165			Pages:	7
		Recorded:	07/20/2017
Conveyance:	CHANGE OF NAME (SEE DOCUMENT FOR DETAILS).

Total properties: 40

Patent #:	NONE	Issue Dt:		Application #:	12957340	Filing Dt:	11/30/2010
Publication #:	US20110244026	Pub Dt:	10/06/2011
Title:	DELIVERY OF MRNA FOR THE AUGMENTATION OF PROTEINS AND ENZYMES IN HUMAN GENETIC DISEASES

Patent #:	8853377	Issue Dt:	10/07/2014	Application #:	13306781	Filing Dt:	11/29/2011
Publication #:	US20120142756	Pub Dt:	06/07/2012
Title:	MRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES

Patent #:	10143758	Issue Dt:	12/04/2018	Application #:	13800501	Filing Dt:	03/13/2013
Publication #:	US20130195967	Pub Dt:	08/01/2013
Title:	LIVER SPECIFIC DELIVERY OF MESSENGER RNA

Patent #:	NONE	Issue Dt:		Application #:	14124608	Filing Dt:	03/05/2014
Publication #:	US20140206753	Pub Dt:	07/24/2014
Title:	LIPID NANOPARTICLE COMPOSITIONS AND METHODS FOR MRNA DELIVERY

Patent #:	9717690	Issue Dt:	08/01/2017	Application #:	14124615	Filing Dt:	06/04/2014
Publication #:	US20140288160	Pub Dt:	09/25/2014
Title:	CLEAVABLE LIPIDS

Patent #:	9181321	Issue Dt:	11/10/2015	Application #:	14307322	Filing Dt:	06/17/2014
Publication #:	US20150038556	Pub Dt:	02/05/2015
Title:	CFTR MRNA COMPOSITIONS AND RELATED METHODS AND USES

Patent #:	9308281	Issue Dt:	04/12/2016	Application #:	14308546	Filing Dt:	06/18/2014
Publication #:	US20140294938	Pub Dt:	10/02/2014
Title:	MRNA THERAPY FOR FABRY DISEASE

Patent #:	9597413	Issue Dt:	03/21/2017	Application #:	14308554	Filing Dt:	06/18/2014
Publication #:	US20140294939	Pub Dt:	10/02/2014
Title:	PULMONARY DELIVERY OF MRNA

Patent #:	NONE	Issue Dt:		Application #:	14309387	Filing Dt:	06/19/2014
Publication #:	US20140294940	Pub Dt:	10/02/2014
Title:	MRNA THERAPY FOR UREA CYCLE DISORDERS

Patent #:	9061021	Issue Dt:	06/23/2015	Application #:	14325594	Filing Dt:	07/08/2014
Publication #:	US20150004217	Pub Dt:	01/01/2015
Title:	mRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES

Patent #:	9546128	Issue Dt:	01/17/2017	Application #:	14389023	Filing Dt:	09/29/2014
Publication #:	US20150166462	Pub Dt:	06/18/2015
Title:	IONIZABLE CATIONIC LIPIDS

Patent #:	9877919	Issue Dt:	01/30/2018	Application #:	14389165	Filing Dt:	09/29/2014
Publication #:	US20150086613	Pub Dt:	03/26/2015
Title:	LIPID-DERIVED NEUTRAL NANOPARTICLES

Patent #:	NONE	Issue Dt:		Application #:	14406424	Filing Dt:	12/08/2014
Publication #:	US20150267192	Pub Dt:	09/24/2015
Title:	NUCLEASE RESISTANT POLYNUCLEOTIDES AND USES THEREOF

Patent #:	10245229	Issue Dt:	04/02/2019	Application #:	14406504	Filing Dt:	12/08/2014
Publication #:	US20150157565	Pub Dt:	06/11/2015
Title:	PULMONARY DELIVERY OF MRNA TO NON-LUNG TARGET CELLS

Patent #:	9629804	Issue Dt:	04/25/2017	Application #:	14521161	Filing Dt:	10/22/2014
Publication #:	US20150140070	Pub Dt:	05/21/2015
Title:	LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA

Patent #:	NONE	Issue Dt:		Application #:	14521168	Filing Dt:	10/22/2014
Publication #:	US20150110857	Pub Dt:	04/23/2015
Title:	CNS DELIVERY OF MRNA AND USES THEREOF

Patent #:	9522176	Issue Dt:	12/20/2016	Application #:	14521323	Filing Dt:	10/22/2014
Publication #:	US20150110858	Pub Dt:	04/23/2015
Title:	MRNA THERAPY FOR PHENYLKETONURIA

Patent #:	11224642	Issue Dt:	01/18/2022	Application #:	14521351	Filing Dt:	10/22/2014
Publication #:	US20150110859	Pub Dt:	04/23/2015
Title:	MRNA THERAPY FOR ARGININOSUCCINATE SYNTHETASE DEFICIENCY

Patent #:	NONE	Issue Dt:		Application #:	14650104	Filing Dt:	06/05/2015
Publication #:	US20150366997	Pub Dt:	12/24/2015
Title:	COMPOSITIONS AND METHODS FOR mRNA DELIVERY

Patent #:	9850269	Issue Dt:	12/26/2017	Application #:	14696140	Filing Dt:	04/24/2015
Publication #:	US20150376220	Pub Dt:	12/31/2015
Title:	METHODS FOR PURIFICATION OF MESSENGER RNA

Patent #:	9956271	Issue Dt:	05/01/2018	Application #:	14714871	Filing Dt:	05/18/2015
Publication #:	US20160101160	Pub Dt:	04/14/2016
Title:	mRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES

Patent #:	10138213	Issue Dt:	11/27/2018	Application #:	14749027	Filing Dt:	06/24/2015
Publication #:	US20150376144	Pub Dt:	12/31/2015
Title:	STEREOCHEMICALLY ENRICHED COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS

Patent #:	NONE	Issue Dt:		Application #:	14774263	Filing Dt:	02/19/2016
Publication #:	US20160184458	Pub Dt:	06/30/2016
Title:	MRNA THERAPEUTIC COMPOSITIONS AND USE TO TREAT DISEASES AND DISORDERS

Patent #:	10130649	Issue Dt:	11/20/2018	Application #:	14775818	Filing Dt:	09/14/2015
Publication #:	US20160151409	Pub Dt:	06/02/2016
Title:	SYNERGISTIC ENHANCEMENT OF THE DELIVERY OF NUCLEIC ACIDS VIA BLENDED FORMULATIONS

Patent #:	10087247	Issue Dt:	10/02/2018	Application #:	14775835	Filing Dt:	09/14/2015
Publication #:	US20160031981	Pub Dt:	02/04/2016
Title:	METHODS AND COMPOSITIONS FOR DELIVERING MRNA CODED ANTIBODIES

Patent #:	10626439	Issue Dt:	04/21/2020	Application #:	14775844	Filing Dt:	09/14/2015
Publication #:	US20160002705	Pub Dt:	01/07/2016
Title:	QUANTITATIVE ASSESSMENT FOR CAP EFFICIENCY OF MESSENGER RNA

Patent #:	9970047	Issue Dt:	05/15/2018	Application #:	14775846	Filing Dt:	09/14/2015
Publication #:	US20160032356	Pub Dt:	02/04/2016
Title:	QUANTITATIVE ASSESSMENT FOR CAP EFFICIENCY OF MESSENGER RNA

Patent #:	9957499	Issue Dt:	05/01/2018	Application #:	14775915	Filing Dt:	09/14/2015
Publication #:	US20160040154	Pub Dt:	02/11/2016
Title:	METHODS FOR PURIFICATION OF MESSENGER RNA

Patent #:	10266559	Issue Dt:	04/23/2019	Application #:	14776506	Filing Dt:	09/14/2015
Publication #:	US20160031928	Pub Dt:	02/04/2016
Title:	RIBONUCLEIC ACIDS WITH 4'-THIO-MODIFIED NUCLEOTIDES AND RELATED METHODS

Patent #:	9668980	Issue Dt:	06/06/2017	Application #:	14790562	Filing Dt:	07/02/2015
Publication #:	US20160038432	Pub Dt:	02/11/2016
Title:	ENCAPSULATION OF MESSENGER RNA

Patent #:	9713626	Issue Dt:	07/25/2017	Application #:	14876071	Filing Dt:	10/06/2015
Publication #:	US20160106772	Pub Dt:	04/21/2016
Title:	CFTR MRNA COMPOSITIONS AND RELATED METHODS AND USES

Patent #:	NONE	Issue Dt:		Application #:	14898071	Filing Dt:	12/11/2015
Publication #:	US20160122727	Pub Dt:	05/05/2016
Title:	MESSENGER RNA BASED VIRAL PRODUCTION

Patent #:	9943595	Issue Dt:	04/17/2018	Application #:	14959453	Filing Dt:	12/04/2015
Publication #:	US20160158354	Pub Dt:	06/09/2016
Title:	MESSENGER RNA THERAPY FOR TREATMENT OF ARTICULAR DISEASE

Patent #:	10172924	Issue Dt:	01/08/2019	Application #:	15073163	Filing Dt:	03/17/2016
Publication #:	US20160324940	Pub Dt:	11/10/2016
Title:	MRNA THERAPY FOR POMPE DISEASE

Patent #:	10576166	Issue Dt:	03/03/2020	Application #:	15092226	Filing Dt:	04/06/2016
Publication #:	US20160287725	Pub Dt:	10/06/2016
Title:	LIVER SPECIFIC DELIVERY OF MESSENGER RNA

Patent #:	NONE	Issue Dt:		Application #:	15128303	Filing Dt:	09/22/2016
Publication #:	US20170143848	Pub Dt:	05/25/2017
Title:	MRNA THERAPY FOR THE TREATMENT OF OCULAR DISEASES

Patent #:	10144942	Issue Dt:	12/04/2018	Application #:	15294249	Filing Dt:	10/14/2016
Publication #:	US20170159093	Pub Dt:	06/08/2017
Title:	MODIFICATION OF RNA-RELATED ENZYMES FOR ENHANCED PRODUCTION

Patent #:	10022455	Issue Dt:	07/17/2018	Application #:	15314818	Filing Dt:	11/29/2016
Publication #:	US20170246319	Pub Dt:	08/31/2017
Title:	BIODEGRADABLE LIPIDS FOR DELIVERY OF NUCLEIC ACIDS

Patent #:	10208295	Issue Dt:	02/19/2019	Application #:	15349720	Filing Dt:	11/11/2016
Publication #:	US20170073648	Pub Dt:	03/16/2017
Title:	MRNA THERAPY FOR PHENYLKETONURIA

Patent #:	10065919	Issue Dt:	09/04/2018	Application #:	15368280	Filing Dt:	12/02/2016
Publication #:	US20170240501	Pub Dt:	08/24/2017
Title:	IONIZABLE CATIONIC LIPIDS

Assignor

RANA THERAPEUTICS, INC.

Exec Dt:

06/26/2017

Assignee

TRANSLATE BIO, INC.

200 SIDNEY STREET

CAMBRIDGE, MASSACHUSETTS 02139

Correspondence name and address
	PROSKAUER ROSE LLP
	ONE INTERNATIONAL PLACE
	BOSTON, MA 02110

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