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Reel/Frame:	063362/0550			Pages:	73
		Recorded:	04/18/2023
Attorney Dkt #:	687747.0071
Conveyance:	RELEASE OF GRANT OF SECURITY INTEREST IN PATENTS

Total properties: 69

Patent #:	5985848	Issue Dt:	11/16/1999	Application #:	08949388	Filing Dt:	10/14/1997
Title:	INHIBITORS OF NUCLEOSIDE METABOLISM

Patent #:	6066722	Issue Dt:	05/23/2000	Application #:	09172321	Filing Dt:	10/14/1998
Title:	INHIBITORS OF NUCLEOSIDE METABOLISM

Patent #:	6228847	Issue Dt:	05/08/2001	Application #:	09496741	Filing Dt:	02/03/2000
Title:	Inhibitors of nucleoside metabolism

Patent #:	6562861	Issue Dt:	05/13/2003	Application #:	09555131	Filing Dt:	05/25/2000
Title:	SUBSTITUTED CYCLOPENTANE AND CYCLOPENTENE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS

Patent #:	6492347	Issue Dt:	12/10/2002	Application #:	09820276	Filing Dt:	03/28/2001
Publication #:	US20020061898	Pub Dt:	05/23/2002
Title:	INHIBITORS OF NUCLEOSIDE METABOLISM

Patent #:	6503745	Issue Dt:	01/07/2003	Application #:	09831140	Filing Dt:	05/07/2001
Title:	CYCLOPENTANE AND CYCLOPENTENE COMPOUNDS AND USE FOR DETECTING INFLUENZA VIRUS

Patent #:	6458799	Issue Dt:	10/01/2002	Application #:	09847998	Filing Dt:	05/04/2001
Title:	DEAZAGUANINE ANALOG, PREPARATION THEREOF AND USE THEREOF

Patent #:	6693193	Issue Dt:	02/17/2004	Application #:	09958219	Filing Dt:	04/18/2002
Title:	PROCESS FOR PREPARING 2-PYRROLIDINYL-1H-PYRROLO[3,2-D]PYRIMIDINE INHIBITORS OF NUCLEOSIDE METABOLISM

Patent #:	6576786	Issue Dt:	06/10/2003	Application #:	09991753	Filing Dt:	11/26/2001
Publication #:	US20020061930	Pub Dt:	05/23/2002
Title:	PROCESS FOR PREPARING SUBSTITUTED CYCLOPENTANE DERIVATIVES AND NOVEL CRYSTALLINE STRUCTURES THEREOF

Patent #:	6660719	Issue Dt:	12/09/2003	Application #:	10016108	Filing Dt:	12/17/2001
Publication #:	US20030114466	Pub Dt:	06/19/2003
Title:	INHIBITING T-CELL PROLIFERATION

Patent #:	6762316	Issue Dt:	07/13/2004	Application #:	10019217	Filing Dt:	05/13/2002
Title:	PREPARATION OF SUBSTITUTED CYCLOPENTANE AND CYCLOPENTENE COMPOUNDS AND CERTAIN INTERMEDIATES

Patent #:	6495711	Issue Dt:	12/17/2002	Application #:	10020402	Filing Dt:	12/18/2001
Publication #:	US20020052524	Pub Dt:	05/02/2002
Title:	PROCESS FOR PREPARING (-)-(1S, 4R) N-PROTECTED 4-AMINO-2-CYCLOPENTENE-1-CARBOXYLATE ESTERS

Patent #:	6699994	Issue Dt:	03/02/2004	Application #:	10127460	Filing Dt:	04/23/2002
Title:	BIARYL COMPOUNDS AS SERINE PROTEASE INHIBITORS

Patent #:	6803455	Issue Dt:	10/12/2004	Application #:	10268652	Filing Dt:	10/10/2002
Publication #:	US20030096830	Pub Dt:	05/22/2003
Title:	INHIBITORS OF NUCLEOSIDE METABOLISM

Patent #:	6780993	Issue Dt:	08/24/2004	Application #:	10367950	Filing Dt:	02/19/2003
Title:	PREPARATION OF DEAZAGUANINE ANALOG

Patent #:	6972331	Issue Dt:	12/06/2005	Application #:	10420757	Filing Dt:	04/23/2003
Publication #:	US20040214840	Pub Dt:	10/28/2004
Title:	CARBOXY PYRROLE, PROCESS OF PREPARING AND USE AS PRECURSOR

Patent #:	7553839	Issue Dt:	06/30/2009	Application #:	10524995	Filing Dt:	09/27/2005
Publication #:	US20060160765	Pub Dt:	07/20/2006
Title:	5H-PYRROLO[3,2-D] PYRIMIDINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND NUCLEOSIDASES

Patent #:	7022852	Issue Dt:	04/04/2006	Application #:	10737724	Filing Dt:	12/16/2003
Publication #:	US20040181063	Pub Dt:	09/16/2004
Title:	PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE METABOLISM

Patent #:	6936719	Issue Dt:	08/30/2005	Application #:	10738027	Filing Dt:	12/18/2003
Publication #:	US20040162281	Pub Dt:	08/19/2004
Title:	BIARYL COMPOUNDS AS SERINE PROTEASE INHIBITORS

Patent #:	7211653	Issue Dt:	05/01/2007	Application #:	10932841	Filing Dt:	09/02/2004
Publication #:	US20050026936	Pub Dt:	02/03/2005
Title:	INHIBITORS OF NUCLEOSIDE METABOLISM

Patent #:	7560434	Issue Dt:	07/14/2009	Application #:	11157867	Filing Dt:	06/22/2005
Publication #:	US20070099942	Pub Dt:	05/03/2007
Title:	AZA NUCLEOSIDES, PREPARATION THEREOF AND USE AS INHIBITORS OF RNA VIRAL POLYMERASES

Patent #:	7230119	Issue Dt:	06/12/2007	Application #:	11210691	Filing Dt:	08/25/2005
Publication #:	US20060128789	Pub Dt:	06/15/2006
Title:	PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRROLIDINE DERIVATIVES AND INTERMEDIATES

Patent #:	7388002	Issue Dt:	06/17/2008	Application #:	11269819	Filing Dt:	11/09/2005
Publication #:	US20060122391	Pub Dt:	06/08/2006
Title:	NUCLEOSIDES, PREPARATION THEREOF AND USE AS INHIBITORS OF RNA VIRAL POLYMERASES

Patent #:	7211677	Issue Dt:	05/01/2007	Application #:	11297954	Filing Dt:	12/08/2005
Publication #:	US20060089498	Pub Dt:	04/27/2006
Title:	PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE METABOLISM

Patent #:	7429571	Issue Dt:	09/30/2008	Application #:	11332858	Filing Dt:	01/16/2006
Publication #:	US20060165655	Pub Dt:	07/27/2006
Title:	THERAPEUTIC FUROPYRIMIDINES AND THIENOPYRIMIDINES

Patent #:	7514410	Issue Dt:	04/07/2009	Application #:	11388060	Filing Dt:	03/23/2006
Publication #:	US20060234963	Pub Dt:	10/19/2006
Title:	HEPATITIS C THERAPIES

Patent #:	7405297	Issue Dt:	07/29/2008	Application #:	11716100	Filing Dt:	03/09/2007
Publication #:	US20070161667	Pub Dt:	07/12/2007
Title:	PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE METABOLISM

Patent #:	7390890	Issue Dt:	06/24/2008	Application #:	11728730	Filing Dt:	03/26/2007
Publication #:	US20070197561	Pub Dt:	08/23/2007
Title:	INHIBITORS OF NUCLEOSIDE METABOLISM

Patent #:	8344132	Issue Dt:	01/01/2013	Application #:	11916146	Filing Dt:	12/08/2009
Publication #:	US20100093991	Pub Dt:	04/15/2010
Title:	METHODS FOR THE PREPARATION OF 9-DEAZAPURINE DERIVATIVES

Patent #:	8853224	Issue Dt:	10/07/2014	Application #:	12310708	Filing Dt:	09/29/2009
Publication #:	US20110130412	Pub Dt:	06/02/2011
Title:	ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES

Patent #:	8163703	Issue Dt:	04/24/2012	Application #:	12399521	Filing Dt:	03/06/2009
Publication #:	US20100143300	Pub Dt:	06/10/2010
Title:	HEPATITIS C THERAPIES

Patent #:	8173662	Issue Dt:	05/08/2012	Application #:	12455537	Filing Dt:	06/03/2009
Publication #:	US20090239885	Pub Dt:	09/24/2009
Title:	FUSED PYRIMIDINES AS INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND NUCLEOSIDASES

Patent #:	8440813	Issue Dt:	05/14/2013	Application #:	12522892	Filing Dt:	07/30/2009
Publication #:	US20100015094	Pub Dt:	01/21/2010
Title:	ANTIVIRAL NUCLEOSIDE ANALOGS

Patent #:	8242085	Issue Dt:	08/14/2012	Application #:	12599656	Filing Dt:	11/10/2009
Publication #:	US20110002886	Pub Dt:	01/06/2011
Title:	TETRAHYDROFURO [3,4-D] DIOXOLANE COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS AND CANCER

Patent #:	8778997	Issue Dt:	07/15/2014	Application #:	13103562	Filing Dt:	05/09/2011
Publication #:	US20120059057	Pub Dt:	03/08/2012
Title:	ANTIVIRAL TREATMENTS

Patent #:	8501753	Issue Dt:	08/06/2013	Application #:	13258497	Filing Dt:	03/16/2012
Publication #:	US20120165526	Pub Dt:	06/28/2012
Title:	USEFUL PHARMACEUTICAL SALTS OF 7- [(3R, 4R) - 3 - HYDROXY -4 - HYDROXYMETHYL - PYRROLIDIN -1- YLMETHYL] -3, 5-DIHYDRO-PYRROLO [3, 2-D] PYRIMIDIN -4-ONE

Patent #:	9770427	Issue Dt:	09/26/2017	Application #:	14313738	Filing Dt:	06/24/2014
Publication #:	US20140309301	Pub Dt:	10/16/2014
Title:	ANTIVIRAL TREATMENTS

Patent #:	9580428	Issue Dt:	02/28/2017	Application #:	14395355	Filing Dt:	10/17/2014
Publication #:	US20150191472	Pub Dt:	07/09/2015
Title:	COMPOSITIONS AND METHODS FOR INHIBITING VIRAL POLYMERASE

Patent #:	9492452	Issue Dt:	11/15/2016	Application #:	14531471	Filing Dt:	11/03/2014
Publication #:	US20150051230	Pub Dt:	02/19/2015
Title:	Methods and Compositions for Inhibition of Polymerase

Patent #:	9499554	Issue Dt:	11/22/2016	Application #:	14890719	Filing Dt:	11/12/2015
Publication #:	US20160096842	Pub Dt:	04/07/2016
Title:	ANTI-INFLUENZA COMPOSITIONS AND METHODS

Patent #:	10125102	Issue Dt:	11/13/2018	Application #:	15123059	Filing Dt:	09/01/2016
Publication #:	US20170073314	Pub Dt:	03/16/2017
Title:	HUMAN PLASMA KALLIKREIN INHIBITORS

Patent #:	10022375	Issue Dt:	07/17/2018	Application #:	15337320	Filing Dt:	10/28/2016
Publication #:	US20170042901	Pub Dt:	02/16/2017
Title:	METHODS AND COMPOSITIONS FOR INHIBITION OF POLYMERASE

Patent #:	10905683	Issue Dt:	02/02/2021	Application #:	15505534	Filing Dt:	02/21/2017
Publication #:	US20170266172	Pub Dt:	09/21/2017
Title:	Compositions and Uses of Amidine Derivatives

Patent #:	10391075	Issue Dt:	08/27/2019	Application #:	15714918	Filing Dt:	09/25/2017
Publication #:	US20180015063	Pub Dt:	01/18/2018
Title:	ANTIVIRAL TREATMENTS

Patent #:	10562850	Issue Dt:	02/18/2020	Application #:	15764071	Filing Dt:	03/28/2018
Publication #:	US20180362458	Pub Dt:	12/20/2018
Title:	HUMAN PLASMA KALLIKREIN INHIBITORS

Patent #:	10329260	Issue Dt:	06/25/2019	Application #:	15977129	Filing Dt:	05/11/2018
Publication #:	US20180258049	Pub Dt:	09/13/2018
Title:	HUMAN PLASMA KALLIKREIN INHIBITORS

Patent #:	10633345	Issue Dt:	04/28/2020	Application #:	16009943	Filing Dt:	06/15/2018
Publication #:	US20180354906	Pub Dt:	12/13/2018
Title:	HUMAN PLASMA KALLIKREIN INHIBITORS

Patent #:	10420769	Issue Dt:	09/24/2019	Application #:	16013059	Filing Dt:	06/20/2018
Publication #:	US20180360836	Pub Dt:	12/20/2018
Title:	METHODS AND COMPOSITIONS FOR INHIBITION OF POLYMERASE

Patent #:	10849883	Issue Dt:	12/01/2020	Application #:	16073934	Filing Dt:	07/30/2018
Publication #:	US20190142802	Pub Dt:	05/16/2019
Title:	BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF

Patent #:	10512649	Issue Dt:	12/24/2019	Application #:	16082437	Filing Dt:	09/05/2018
Publication #:	US20190083496	Pub Dt:	03/21/2019
Title:	METHODS AND COMPOSITIONS FOR TREATMENT OF ZIKA VIRUS INFECTION

Patent #:	10759759	Issue Dt:	09/01/2020	Application #:	16345503	Filing Dt:	04/26/2019
Publication #:	US20190382344	Pub Dt:	12/19/2019
Title:	PRODRUGS OF KALLIKREIN INHIBITORS

Patent #:	11110092	Issue Dt:	09/07/2021	Application #:	16400414	Filing Dt:	05/01/2019
Publication #:	US20190255058	Pub Dt:	08/22/2019
Title:	METHODS OF TREATING HEMATOLOGIC CANCERS

Patent #:	10689346	Issue Dt:	06/23/2020	Application #:	16400798	Filing Dt:	05/01/2019
Publication #:	US20190322626	Pub Dt:	10/24/2019
Title:	HUMAN PLASMA KALLIKREIN INHIBITORS

Patent #:	11021458	Issue Dt:	06/01/2021	Application #:	16511642	Filing Dt:	07/15/2019
Publication #:	US20190345135	Pub Dt:	11/14/2019
Title:	SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS

Patent #:	11464755	Issue Dt:	10/11/2022	Application #:	16533283	Filing Dt:	08/06/2019
Publication #:	US20190358187	Pub Dt:	11/28/2019
Title:	ANTIVIRAL TREATMENTS

Patent #:	11173159	Issue Dt:	11/16/2021	Application #:	16543079	Filing Dt:	08/16/2019
Publication #:	US20190374544	Pub Dt:	12/12/2019
Title:	METHODS AND COMPOSITIONS FOR INHIBITION OF POLYMERASE

Patent #:	11661426	Issue Dt:	05/30/2023	Application #:	16622816	Filing Dt:	12/13/2019
Publication #:	US20220332723	Pub Dt:	10/20/2022
Title:	IMIDAZOLE-CONTAINING INHIBITORS OF ALK2 KINASE

Patent #:	10662160	Issue Dt:	05/26/2020	Application #:	16671649	Filing Dt:	11/01/2019
Publication #:	US20200140389	Pub Dt:	05/07/2020
Title:	CRYSTALLINE SALTS OF A PLASMA KALLIKREIN INHIBITOR

Patent #:	10933066	Issue Dt:	03/02/2021	Application #:	16692816	Filing Dt:	11/22/2019
Publication #:	US20200085830	Pub Dt:	03/19/2020
Title:	METHODS AND COMPOSITIONS FOR TREATMENT OF ZIKA VIRUS INFECTION

Patent #:	11066360	Issue Dt:	07/20/2021	Application #:	16718537	Filing Dt:	12/18/2019
Publication #:	US20200361867	Pub Dt:	11/19/2020
Title:	HUMAN PLASMA KALLIKREIN INHIBITORS

Patent #:	11117867	Issue Dt:	09/14/2021	Application #:	16784016	Filing Dt:	02/06/2020
Publication #:	US20200308118	Pub Dt:	10/01/2020
Title:	CRYSTALLINE SALTS OF A PLASMA KALLIKREIN INHIBITOR

Patent #:	11192861	Issue Dt:	12/07/2021	Application #:	16828755	Filing Dt:	03/24/2020
Publication #:	US20210047275	Pub Dt:	02/18/2021
Title:	HUMAN PLASMA KALLIKREIN INHIBITORS

Patent #:	11203574	Issue Dt:	12/21/2021	Application #:	16828763	Filing Dt:	03/24/2020
Publication #:	US20210047276	Pub Dt:	02/18/2021
Title:	HUMAN PLASMA KALLIKREIN INHIBITORS

Patent #:	11230530	Issue Dt:	01/25/2022	Application #:	16845833	Filing Dt:	04/10/2020
Publication #:	US20210078952	Pub Dt:	03/18/2021
Title:	HUMAN PLASMA KALLIKREIN INHIBITORS

Patent #:	11618731	Issue Dt:	04/04/2023	Application #:	16987721	Filing Dt:	08/07/2020
Publication #:	US20210198204	Pub Dt:	07/01/2021
Title:	PRODRUGS OF KALLIKREIN INHIBITORS

Patent #:	11559515	Issue Dt:	01/24/2023	Application #:	17003552	Filing Dt:	08/26/2020
Publication #:	US20210260035	Pub Dt:	08/26/2021
Title:	INDOLE COMPOUNDS AND ANALOGUES THEREOF

Patent #:	NONE	Issue Dt:		Application #:	17602674	Filing Dt:	10/08/2021
Publication #:	US20220160694	Pub Dt:	05/26/2022			PCT #:	US2020027287
Title:	PLASMA KALLIKREIN INHIBITORS AND METHODS OF USE THEREOF IN OCULAR DISORDERS

Patent #:	NONE	Issue Dt:		Application #:	17630692	Filing Dt:	01/27/2022
Publication #:	US20220257556	Pub Dt:	08/18/2022			PCT #:	US2020044037
Title:	DOSING REGIMENS FOR ORAL COMPLEMENT FACTOR D INHIBITORS

Patent #:	NONE	Issue Dt:		Application #:	17632585	Filing Dt:	02/03/2022
Publication #:	US20220289683	Pub Dt:	09/15/2022			PCT #:	US2020044921
Title:	PROCESS-SCALE SYNTHESIS OF A PLASMA KALLIKREIN INHIBITOR

Assignor

ATHYRIUM OPPORTUNITIES III CO-INVEST 1 LP

Exec Dt:

04/17/2023

Assignee

BIOCRYST PHARMACEUTICALS, INC.

4505 EMPEROR BLVD

DURHAM, NORTH CAROLINA 27703

Correspondence name and address
	MUSSIE B BEYENE
	2001 K STREET N.W.
	WASHINGTON DC, DC 20006

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