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Reel/Frame:	023348/0621			Pages:	10
		Recorded:	10/09/2009
Attorney Dkt #:	16534-001
Conveyance:	RELEASE BY SECURED PARTY (SEE DOCUMENT FOR DETAILS).

Total properties: 79

Patent #:	5817793	Issue Dt:	10/06/1998	Application #:	08225480	Filing Dt:	04/08/1994
Title:	MULTIPLE ANTIBIOTIC RESISTANCE OPERON ASSAYS

Patent #:	5650321	Issue Dt:	07/22/1997	Application #:	08379698	Filing Dt:	01/27/1995
Title:	IDENTIFICATION AND ISOLATION OF NEW GENES OF A BACTERIAL MULTIPLE ANTIBIOTIC RESISTANCE REGULON

Patent #:	5766924	Issue Dt:	06/16/1998	Application #:	08897357	Filing Dt:	07/21/1997
Title:	IDENTIFICATION AND ISOLATION OF NEW GENES OF A BACTERIAL MULTIPLE ANTIBIOTIC RESISTANCE REGULON

Patent #:	6068972	Issue Dt:	05/30/2000	Application #:	08946225	Filing Dt:	10/07/1997
Title:	METHODS AND COMPOSITIONS FOR REDUCING BACTERIAL TOLERANCE TO ANTIBACTERIALS, DISINFECTANTS AND ORGANIC SOLVENTS

Patent #:	6136602	Issue Dt:	10/24/2000	Application #:	09027130	Filing Dt:	02/20/1998
Title:	OLIGONUCLEOTIDES SPECIFIC FOR THE MARORAB OPERON

Patent #:	6391545	Issue Dt:	05/21/2002	Application #:	09118445	Filing Dt:	07/17/1998
Title:	MULTIPLE ANTIBIOTIC RESISTANCE OPERON ASSAYS

Patent #:	6346391	Issue Dt:	02/12/2002	Application #:	09358948	Filing Dt:	07/22/1999
Title:	METHODS OF REDUCING MICROBIAL RESISTANCE TO DRUGS

Patent #:	6448006	Issue Dt:	09/10/2002	Application #:	09515705	Filing Dt:	02/29/2000
Title:	METHODS AND COMPOSITIONS FOR REDUCING BACTERIAL TOLERANCE TO ANTIBACTERIALS, DISINFECTANTS AND ORGANIC SOLVENTS

Patent #:	6485973	Issue Dt:	11/26/2002	Application #:	09596390	Filing Dt:	06/16/2000
Title:	OLIGONUCLEOTIDES SPECIFIC FOR THE MARORAB OPERON

Patent #:	6818634	Issue Dt:	11/16/2004	Application #:	09823884	Filing Dt:	03/30/2001
Publication #:	US20020103171	Pub Dt:	08/01/2002
Title:	7-AND 9- CARBAMATE, UREA, THIOUREA, THIOCARBAMATE, AND HETEROARYL-AMINO SUBSTITUTED TETRACYCLINE COMPOUNDS

Patent #:	6642270	Issue Dt:	11/04/2003	Application #:	09852908	Filing Dt:	05/10/2001
Publication #:	US20020045602	Pub Dt:	04/18/2002
Title:	7-SUBSTITUTED FUSED RING TETRACYCLINE COMPOUNDS

Patent #:	6500812	Issue Dt:	12/31/2002	Application #:	09895796	Filing Dt:	06/29/2001
Publication #:	US20020147182	Pub Dt:	10/10/2002
Title:	13-SUBSTITUTED METHACYCLINE COMPOUNDS

Patent #:	6683068	Issue Dt:	01/27/2004	Application #:	09895797	Filing Dt:	06/29/2001
Publication #:	US20020193354	Pub Dt:	12/19/2002
Title:	7, 9-SUBSTITUTED TETRACYCLINE COMPOUNDS

Patent #:	6818635	Issue Dt:	11/16/2004	Application #:	09895812	Filing Dt:	06/29/2001
Publication #:	US20030055025	Pub Dt:	03/20/2003
Title:	7-SUBSTITUTED TETRACYCLINE COMPOUNDS

Patent #:	6846939	Issue Dt:	01/25/2005	Application #:	09895857	Filing Dt:	06/29/2001
Publication #:	US20030125348	Pub Dt:	07/03/2003
Title:	9-SUBSTITUTED MINOCYCLINE COMPOUNDS

Patent #:	6677133	Issue Dt:	01/13/2004	Application #:	09966835	Filing Dt:	09/28/2001
Publication #:	US20020132814	Pub Dt:	09/19/2002
Title:	METHODS OF REDUCING MICROBIAL RESISTANCE TO DRUGS

Patent #:	6841546	Issue Dt:	01/11/2005	Application #:	10097457	Filing Dt:	03/14/2002
Publication #:	US20030100017	Pub Dt:	05/29/2003
Title:	SUBSTITUTED TETRACYCLINE COMPOUNDS AS ANTIFUNGAL AGENTS

Patent #:	7045507	Issue Dt:	05/16/2006	Application #:	10097634	Filing Dt:	03/14/2002
Publication #:	US20030166585	Pub Dt:	09/04/2003
Title:	SUBSTITUTED TETRACYCLINE COMPOUNDS AS SYNERGISTIC ANTIFUNGAL AGENTS

Patent #:	7202339	Issue Dt:	04/10/2007	Application #:	10196655	Filing Dt:	07/15/2002
Publication #:	US20030148492	Pub Dt:	08/07/2003
Title:	CRYSTALS OF MARR POLYPEPTIDES, REGULATORS OF MULTIPLE ANTIBIOTIC RESISTANCE

Patent #:	7075582	Issue Dt:	07/11/2006	Application #:	10196672	Filing Dt:	07/15/2002
Publication #:	US20030215873	Pub Dt:	11/20/2003
Title:	METHODS FOR IDENTIFYING AND USING MARR FAMILY POLYPEPTIDE BINDING COMPOUNDS

Patent #:	6849615	Issue Dt:	02/01/2005	Application #:	10285975	Filing Dt:	11/01/2002
Publication #:	US20030166952	Pub Dt:	09/04/2003
Title:	13-SUBSTITUTED METHACYCLINE COMPOUNDS

Patent #:	7056902	Issue Dt:	06/06/2006	Application #:	10337914	Filing Dt:	01/06/2003
Publication #:	US20040157806	Pub Dt:	08/12/2004
Title:	4-DEDIMETHYLAMINO TETRACYCLINE COMPOUNDS

Patent #:	NONE	Issue Dt:		Application #:	10602562	Filing Dt:	06/24/2003
Publication #:	US20040106553	Pub Dt:	06/03/2004
Title:	Methods for preventing and treating microbial infections by modulating transcription factors

Patent #:	7026136	Issue Dt:	04/11/2006	Application #:	10629340	Filing Dt:	07/28/2003
Publication #:	US20050261165	Pub Dt:	11/24/2005
Title:	METHODS OF REDUCING MICROBIAL RESISTANCE TO DRUGS

Patent #:	7208482	Issue Dt:	04/24/2007	Application #:	10636437	Filing Dt:	08/06/2003
Publication #:	US20040192657	Pub Dt:	09/30/2004
Title:	9-AMINOACYL TETRACYCLINE COMPOUNDS AND METHODS OF USE THEREOF

Patent #:	8088820	Issue Dt:	01/03/2012	Application #:	10692563	Filing Dt:	10/24/2003
Publication #:	US20040242548	Pub Dt:	12/02/2004
Title:	SUBSTITUTED TETRACYCLINE COMPOUNDS FOR THE TREATMENT OF MALARIA

Patent #:	8173624	Issue Dt:	05/08/2012	Application #:	10692764	Filing Dt:	10/24/2003
Publication #:	US20040214800	Pub Dt:	10/28/2004
Title:	METHODS OF USING SUBSTITUTED TETRACYCLINE COMPOUNDS TO MODULATE RNA

Patent #:	7405235	Issue Dt:	07/29/2008	Application #:	10700661	Filing Dt:	11/03/2003
Publication #:	US20050124678	Pub Dt:	06/09/2005
Title:	TRANSCRIPTION FACTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF

Patent #:	7326696	Issue Dt:	02/05/2008	Application #:	10737361	Filing Dt:	12/15/2003
Publication #:	US20050026875	Pub Dt:	02/03/2005
Title:	AMINO-METHYL SUBSTITUTED TETRACYCLINE COMPOUNDS

Patent #:	7696186	Issue Dt:	04/13/2010	Application #:	10738862	Filing Dt:	12/16/2003
Publication #:	US20040138183	Pub Dt:	07/15/2004
Title:	7,9-SUBSTITUTED TETRACYCLINE COMPOUNDS

Patent #:	7820641	Issue Dt:	10/26/2010	Application #:	10740961	Filing Dt:	12/18/2003
Publication #:	US20050038002	Pub Dt:	02/17/2005
Title:	SUBSTITUTED TETRACYCLINE COMPOUNDS

Patent #:	NONE	Issue Dt:		Application #:	10742469	Filing Dt:	12/18/2003
Publication #:	US20040229243	Pub Dt:	11/18/2004
Title:	MarA family helix-turn-helix domains and their methods of use

Patent #:	7323492	Issue Dt:	01/29/2008	Application #:	10752378	Filing Dt:	01/05/2004
Publication #:	US20040266740	Pub Dt:	12/30/2004
Title:	7-PYROLLYL 9-AMINOACYL TETRACYCLINE COMPOUNDS AND METHODS OF USE THEREOF

Patent #:	7829543	Issue Dt:	11/09/2010	Application #:	10754041	Filing Dt:	01/07/2004
Publication #:	US20040204378	Pub Dt:	10/14/2004
Title:	SUBSTITUTED POLYAMINES AS INHIBITORS OF BACTERIAL EFFLUX PUMPS

Patent #:	7858600	Issue Dt:	12/28/2010	Application #:	10786710	Filing Dt:	02/24/2004
Publication #:	US20040176334	Pub Dt:	09/09/2004
Title:	7-AND 9- CARBAMATE, UREA, THIOUREA, THIOCARBAMATE, AND HETEROARYL-AMINO SUBSTITUTED TETRACYCLINE COMPOUNDS

Patent #:	7553828	Issue Dt:	06/30/2009	Application #:	10786881	Filing Dt:	02/24/2004
Publication #:	US20050026876	Pub Dt:	02/03/2005
Title:	9-AMINOMETHYL SUBSTITUTED MINOCYCLINE COMPOUNDS

Patent #:	8048867	Issue Dt:	11/01/2011	Application #:	10839023	Filing Dt:	05/04/2004
Publication #:	US20040214801	Pub Dt:	10/28/2004
Title:	9-SUBSTITUTED MINOCYCLINE COMPOUNDS

Patent #:	7595309	Issue Dt:	09/29/2009	Application #:	10853635	Filing Dt:	05/24/2004
Publication #:	US20040224928	Pub Dt:	11/11/2004
Title:	7-SUBSTITUTED TETRACYCLINE COMPOUNDS

Patent #:	7001918	Issue Dt:	02/21/2006	Application #:	10858616	Filing Dt:	06/01/2004
Publication #:	US20040248857	Pub Dt:	12/09/2004
Title:	7-PYRROLYL TETRACYCLINE COMPOUNDS AND METHODS OF USE THEREOF

Patent #:	NONE	Issue Dt:		Application #:	10877928	Filing Dt:	06/25/2004
Publication #:	US20050143352	Pub Dt:	06/30/2005
Title:	Substituted tetracycline compounds

Patent #:	7960366	Issue Dt:	06/14/2011	Application #:	10943571	Filing Dt:	09/16/2004
Publication #:	US20050070510	Pub Dt:	03/31/2005
Title:	SUBSTITUTED TETRACYCLINE COMPOUNDS AS SYNERGISTIC ANTIFUNGAL AGENTS

Patent #:	NONE	Issue Dt:		Application #:	10996119	Filing Dt:	11/22/2004
Publication #:	US20060194773	Pub Dt:	08/31/2006
Title:	Tetracyline compounds having target therapeutic activities

Patent #:	7786099	Issue Dt:	08/31/2010	Application #:	11039230	Filing Dt:	01/18/2005
Publication #:	US20060003971	Pub Dt:	01/05/2006
Title:	AROMATIC A-RING DERIVATIVES OF TETRACYCLINE COMPOUNDS

Patent #:	7825105	Issue Dt:	11/02/2010	Application #:	11069197	Filing Dt:	02/28/2005
Publication #:	US20050288262	Pub Dt:	12/29/2005
Title:	3, 10, AND 12A SUBSTITUTED TETRACYCLINE COMPOUNDS

Patent #:	NONE	Issue Dt:		Application #:	11115024	Filing Dt:	04/25/2005
Publication #:	US20060160799	Pub Dt:	07/20/2006
Title:	Transcription factor modulating compounds and methods of use thereof

Patent #:	7858601	Issue Dt:	12/28/2010	Application #:	11258613	Filing Dt:	10/25/2005
Publication #:	US20060166944	Pub Dt:	07/27/2006
Title:	4-Substituted tetracyclines and methods of use thereof

Patent #:	8466132	Issue Dt:	06/18/2013	Application #:	11258622	Filing Dt:	10/25/2005
Publication #:	US20060166945	Pub Dt:	07/27/2006
Title:	Substituted tetracycline compounds

Patent #:	NONE	Issue Dt:		Application #:	11260676	Filing Dt:	10/26/2005
Publication #:	US20060264517	Pub Dt:	11/23/2006
Title:	Methods of reducing microbial resistance to drugs

Patent #:	NONE	Issue Dt:		Application #:	11283571	Filing Dt:	11/18/2005
Publication #:	US20060089336	Pub Dt:	04/27/2006
Title:	4-Dedimethylamino tetracycline compounds

Patent #:	7696358	Issue Dt:	04/13/2010	Application #:	11292552	Filing Dt:	12/02/2005
Publication #:	US20060084634	Pub Dt:	04/20/2006
Title:	FIVE-MEMBERED HETEROCYCLYL TETRACYCLINE COMPOUNDS AND METHODS OF USE THEREOF

Patent #:	NONE	Issue Dt:		Application #:	11296017	Filing Dt:	12/07/2005
Publication #:	US20060084678	Pub Dt:	04/20/2006
Title:	Methods for identifying and using MarR family polypeptide binding compounds

Patent #:	7612053	Issue Dt:	11/03/2009	Application #:	11305048	Filing Dt:	12/16/2005
Publication #:	US20060148765	Pub Dt:	07/06/2006
Title:	7-SUBSTITUTED FUSED RING TETRACYCLINE COMPOUNDS

Patent #:	NONE	Issue Dt:		Application #:	11330700	Filing Dt:	01/12/2006
Publication #:	US20060287283	Pub Dt:	12/21/2006
Title:	Prodrugs of 9-aminomethyl tetracycline compounds

Patent #:	8088755	Issue Dt:	01/03/2012	Application #:	11348608	Filing Dt:	02/06/2006
Publication #:	US20060281717	Pub Dt:	12/14/2006
Title:	11A, 12-DERIVATIVES OF TETRACYCLINE COMPOUNDS

Patent #:	NONE	Issue Dt:		Application #:	11490867	Filing Dt:	07/21/2006
Publication #:	US20070093455	Pub Dt:	04/26/2007
Title:	10-substituted tetracyclines and methods of use thereof

Patent #:	7652002	Issue Dt:	01/26/2010	Application #:	11643752	Filing Dt:	12/20/2006
Publication #:	US20070270389	Pub Dt:	11/22/2007
Title:	9-AMINOACYL TETRACYCLINE COMPOUNDS AND METHODS OF USE THEREOF

Patent #:	9078811	Issue Dt:	07/14/2015	Application #:	11657412	Filing Dt:	01/24/2007
Publication #:	US20080070873	Pub Dt:	03/20/2008
Title:	Methods of increasing oral bioavailability of tetracyclines

Patent #:	NONE	Issue Dt:		Application #:	11803854	Filing Dt:	05/15/2007
Publication #:	US20080118979	Pub Dt:	05/22/2008
Title:	Methods of regulating expression of genes or of gene products using substituted tetracycline compounds

Patent #:	NONE	Issue Dt:		Application #:	11810336	Filing Dt:	06/05/2007
Publication #:	US20080015169	Pub Dt:	01/17/2008
Title:	Amino-methyl substituted tetracycline compounds

Patent #:	NONE	Issue Dt:		Application #:	11823103	Filing Dt:	06/25/2007
Publication #:	US20090170812	Pub Dt:	07/02/2009
Title:	Transcription factor modulating compounds and methods of use thereof

Patent #:	8440646	Issue Dt:	05/14/2013	Application #:	11870317	Filing Dt:	10/10/2007
Publication #:	US20130109617	Pub Dt:	05/02/2013
Title:	SUBSTITUTED TETRACYCLINE COMPOUNDS FOR TREATMENT OF BACILLUS ANTHRACIS INFECTIONS

Patent #:	8211937	Issue Dt:	07/03/2012	Application #:	11949392	Filing Dt:	12/03/2007
Publication #:	US20090054379	Pub Dt:	02/26/2009
Title:	7-PYROLLYL 9-AMINOACYL TETRACYCLINE COMPOUNDS AND METHODS OF USE THEREOF

Patent #:	8513223	Issue Dt:	08/20/2013	Application #:	11963509	Filing Dt:	12/21/2007
Publication #:	US20080312193	Pub Dt:	12/18/2008
Title:	SUBSTITUTED TETRACYCLINE COMPOUNDS FOR TREATMENT OF INFLAMMATORY SKIN DISORDERS

Patent #:	8318706	Issue Dt:	11/27/2012	Application #:	11963540	Filing Dt:	12/21/2007
Publication #:	US20100305072	Pub Dt:	12/02/2010
Title:	SUBSTITUTED TETRACYCLINE COMPOUNDS

Patent #:	7893282	Issue Dt:	02/22/2011	Application #:	11974019	Filing Dt:	10/10/2007
Publication #:	US20080300424	Pub Dt:	12/04/2008
Title:	7-SUBSTITUTED FUSED RING TETRACYCLINE COMPOUNDS

Patent #:	NONE	Issue Dt:		Application #:	12057357	Filing Dt:	03/27/2008
Publication #:	US20090131481	Pub Dt:	05/21/2009
Title:	Transcription Factor Modulating Compounds and Methods of Use Thereof

Patent #:	NONE	Issue Dt:		Application #:	12069723	Filing Dt:	02/12/2008
Publication #:	US20090131401	Pub Dt:	05/21/2009
Title:	Transcription factor modulating compounds and methods of use thereof

Patent #:	7935687	Issue Dt:	05/03/2011	Application #:	12102623	Filing Dt:	04/14/2008
Publication #:	US20090118269	Pub Dt:	05/07/2009
Title:	METHODS FOR TREATING SPINAL MUSCULAR ATROPHY USING TETRACYCLINE COMPOUNDS

Patent #:	9434680	Issue Dt:	09/06/2016	Application #:	12110627	Filing Dt:	04/28/2008
Publication #:	US20080287401	Pub Dt:	11/20/2008
Title:	Methods for Synthesizing and Purifying Aminoalkyl Tetracycline Compounds

Patent #:	9522872	Issue Dt:	12/20/2016	Application #:	12217709	Filing Dt:	07/07/2008
Publication #:	US20090156842	Pub Dt:	06/18/2009
Title:	Methods for synthesizing substituted tetracycline compounds

Patent #:	8258120	Issue Dt:	09/04/2012	Application #:	12351405	Filing Dt:	01/09/2009
Publication #:	US20090325908	Pub Dt:	12/31/2009
Title:	9-SUBSTITUTED MINOCYCLINE COMPOUNDS

Patent #:	9314475	Issue Dt:	04/19/2016	Application #:	12414615	Filing Dt:	03/30/2009
Publication #:	US20100056638	Pub Dt:	03/04/2010
Title:	Oral and Injectable Formulations of Tetracycline Compounds

Patent #:	NONE	Issue Dt:		Application #:	12423718	Filing Dt:	04/14/2009
Publication #:	US20100022483	Pub Dt:	01/28/2010
Title:	Substituted Tetracycline Compounds

Patent #:	8383610	Issue Dt:	02/26/2013	Application #:	12471758	Filing Dt:	05/26/2009
Publication #:	US20100113399	Pub Dt:	05/06/2010
Title:	SALTS AND POLYMORPHS OF 9-(2,2-DIMETHYLPROPYL-AMINOMETHYL) MINOCYCLINE

Patent #:	NONE	Issue Dt:		Application #:	12473955	Filing Dt:	05/28/2009
Publication #:	US20100113400	Pub Dt:	05/06/2010
Title:	9-Aminomethyl Substituted Minocycline Compounds

Patent #:	8012711	Issue Dt:	09/06/2011	Application #:	12476053	Filing Dt:	06/01/2009
Publication #:	US20090298873	Pub Dt:	12/03/2009
Title:	METHODS OF SCREENING FOR COMPOUNDS THAT REDUCE MICROBIAL RESISTANCE TO FLUOROQUINOLONES

Patent #:	8492365	Issue Dt:	07/23/2013	Application #:	12481368	Filing Dt:	06/09/2009
Publication #:	US20090306022	Pub Dt:	12/10/2009
Title:	7-SUBSTITUTED TETRACYCLINE COMPOUNDS

Patent #:	8039221	Issue Dt:	10/18/2011	Application #:	12486972	Filing Dt:	06/18/2009
Publication #:	US20110015375	Pub Dt:	01/20/2011
Title:	METHODS FOR IDENTIFYING AND USING MARR FAMILY POLYPEPTIDE BINDING COMPOUNDS

Patent #:	NONE	Issue Dt:		Application #:	12488275	Filing Dt:	06/19/2009
Publication #:	US20100298540	Pub Dt:	11/25/2010
Title:	Crystal Structure of a MarR Family Polypeptide

Assignor

MIDCAP FINANCIAL, LLC

Exec Dt:

10/09/2009

Assignee

PARATEK PHARMACEUTICALS, INC.

75 KNEELAND STREET

BOSTON, MASSACHUSETTS 02111

Correspondence name and address
	BRAD SCHELLER
	666 THIRD AVENUE
	MINTZ LEVIN COHN FERRIS GLOVSKY & POPEO
	NEW YORK, NY 10017

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