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Patent Assignment Details

NOTE:Results display only for issued patents and published applications. For pending or abandoned applications please consult USPTO staff.

Reel/Frame:	008933/0844			Pages:	65
		Recorded:	01/29/1998
Conveyance:	SECURITY INTEREST (SEE DOCUMENT FOR DETAILS).

Total properties: 71

Patent #:	5403709	Issue Dt:	04/04/1995	Application #:	07958133	Filing Dt:	10/06/1992
Title:	METHOD FOR SEQUENCING SYNTHETIC OLIGONUCLEOTIDES CONTAINING NON- PHOSPHODIESTER INTERNUCLEOTIDE LINKAGES

Patent #:	5420265	Issue Dt:	05/30/1995	Application #:	07991466	Filing Dt:	12/16/1992
Title:	SEPARATION OF PHOSPHOROTHIOATE OLIGONUCLEOTIDES BY CAPILLARY GEL ELECTROPHORESIS

Patent #:	5643717	Issue Dt:	07/01/1997	Application #:	08032856	Filing Dt:	03/16/1993
Title:	A SUBSTRATE USEFUL FOR SEPARATING MODIFIED OLIGONUCLEOTIDES

Patent #:	5506103	Issue Dt:	04/09/1996	Application #:	08153365	Filing Dt:	11/16/1993
Title:	METHOD FOR DETECTING CHARGED OLIGONUCLEOTIDES IN BIOLOGICAL FLUIDS

Patent #:	5578716	Issue Dt:	11/26/1996	Application #:	08161673	Filing Dt:	12/01/1993
Title:	DNA METHYLTRANSFERASE ANTISENSE OLIGONUCLEOTIDES

Patent #:	5627277	Issue Dt:	05/06/1997	Application #:	08178660	Filing Dt:	01/07/1994
Title:	METHOD FOR ANALYZING OLIGONUCLEOTIDE ANALOGS

Patent #:	5525470	Issue Dt:	06/11/1996	Application #:	08187749	Filing Dt:	01/26/1994
Title:	A MEHTOD OF SEQUENCING OLIGONUCLLEOTIDES

Patent #:	5558992	Issue Dt:	09/24/1996	Application #:	08241062	Filing Dt:	05/11/1994
Title:	DETECTION OF SYNTHETIC OLIGONUCLEOTIDES EXTRACTED FROM BODY FLUIDS OR TISSUES

Patent #:	5801235	Issue Dt:	09/01/1998	Application #:	08249386	Filing Dt:	05/25/1994
Title:	OLIGONUCLEOTIDES WITH ANTI-CYTOMEGALOVIRUS ACTIVITY

Patent #:	5866699	Issue Dt:	02/02/1999	Application #:	08276567	Filing Dt:	07/18/1994
Title:	OLIGONUCLEOTIDES WITH ANTI-MDR-1 GENE ACTIVITY

Patent #:	5554744	Issue Dt:	09/10/1996	Application #:	08311156	Filing Dt:	09/23/1994
Title:	METHOD FOR LOADING SOLID SUPPORTS FOR NUCLEIC ACID SYNTHESIS

Patent #:	5684147	Issue Dt:	11/04/1997	Application #:	08319823	Filing Dt:	10/07/1994
Title:	THERAPEUTIC ANTI-HIV ANTI-VIRAL OLIGONUCLEOTIDES AND PHARMACEUTICAL FORMULATIONS THEREOF

Patent #:	5510475	Issue Dt:	04/23/1996	Application #:	08320835	Filing Dt:	10/07/1994
Title:	OLIGONUCLEOTIDE MULTIPLE REPORTER PRECURSORS

Patent #:	5650502	Issue Dt:	07/22/1997	Application #:	08336526	Filing Dt:	11/09/1994
Title:	RIBOZYME ANALOGS HAVING RIGID NON-NUCLEOTIDIC LINKERS

Patent #:	5691316	Issue Dt:	11/25/1997	Application #:	08341522	Filing Dt:	11/17/1994
Title:	CYCLODEXTRIN CELLULAR DELIVERY SYSTEM FOR OLIGONUCLEOTIDES

Patent #:	5545729	Issue Dt:	08/13/1996	Application #:	08361687	Filing Dt:	12/22/1994
Title:	STABILIZED RIBOZYME ANALOGS

Patent #:	5693466	Issue Dt:	12/02/1997	Application #:	08368243	Filing Dt:	01/03/1995
Title:	DETECTION OF SYNTHETIC OLIGONUCLEOTIDES EXTRACTED FROM BODY FLUIDS OR TISSUES

Patent #:	5731294	Issue Dt:	03/24/1998	Application #:	08378860	Filing Dt:	01/26/1995
Title:	INHIBITION OF NEOVASUCLARIZATION USING VEGF-SPECIFIC OLIGONUCLEOTIDES

Patent #:	5665593	Issue Dt:	09/09/1997	Application #:	08379079	Filing Dt:	01/26/1995
Title:	ANTISENSE OLIGONUCLEOTIDES WHICH COMBAT ABERRANT SPLICING AND METHODS OF USING THE SAME

Patent #:	5639872	Issue Dt:	06/17/1997	Application #:	08398945	Filing Dt:	03/02/1995
Title:	HUMAN VEGF-SPECIFIC OLIGONUCLEOTIDES

Patent #:	5652103	Issue Dt:	07/29/1997	Application #:	08412913	Filing Dt:	03/29/1995
Title:	METHOD FOR SEQUENCING SYNTHETIC OLIGONUCLETIDES CONTAINING NON-PHOSPHODIESTER INTERNUCLEOTIDE LINKAGES

Patent #:	5739308	Issue Dt:	04/14/1998	Application #:	08418123	Filing Dt:	04/06/1995
Title:	INTEGRATED OLIGONUCLEOTIDES

Patent #:	6372427	Issue Dt:	04/16/2002	Application #:	08420672	Filing Dt:	04/12/1995
Title:	COOPERATIVE OLIGONUCLEOTIDES

Patent #:	5639875	Issue Dt:	06/17/1997	Application #:	08430437	Filing Dt:	04/28/1995
Title:	METHODS FOR H-PHOSPHONATE SYNTHESIS OF OLIGONUCLEOTIDES USING TRIPHOSGENE

Patent #:	5929226	Issue Dt:	07/27/1999	Application #:	08436927	Filing Dt:	05/08/1995
Title:	ANTISENSE OLIGONUCLEOTIDE ALKYLPHOSPHONOTHIOATES AND ARYLPHOSPOHONOTHIOATES

Patent #:	5631361	Issue Dt:	05/20/1997	Application #:	08447092	Filing Dt:	05/22/1995
Title:	METHOD OF SYNTHESIZING RADIOISOTOPICALLY LABELED OLIGONUCLETIDES BY DIRECT SOLID-PHASE 5'PHOSPHITYLATION

Patent #:	5808042	Issue Dt:	09/15/1998	Application #:	08447760	Filing Dt:	05/23/1995
Title:	PROCEDURE FOR THE DETRITYLATION OF DMT-OLIGONUCLEOTIDES USING "DOWEX" ION-EXCHANGE RESIN

Patent #:	5750674	Issue Dt:	05/12/1998	Application #:	08448131	Filing Dt:	05/23/1995
Title:	METHODS AND COMPOUNDS FOR THE STEREOSELECTIVE ENRICHMENT OF OLIGONUCLEOTIDE DIASTEREOMERS AND OLIGONUCLEOTIDES THEREBY PRODUCED

Patent #:	5627274	Issue Dt:	05/06/1997	Application #:	08453224	Filing Dt:	05/30/1995
Title:	ANTISENSE OLIGONUCLEOTIDES WHICH COMBAT ABERRANT SPLICING AND METHODS OF USING THE SAME

Patent #:	5670634	Issue Dt:	09/23/1997	Application #:	08456420	Filing Dt:	06/01/1995
Title:	REVERSAL OF B/A4 AMYLOID PEPTIDE INDUCED MORPHOLOGICAL CHANGES IN NEURONAL CELLS BY ANTISENSE OLIGONUCLEOTIDES

Patent #:	5637464	Issue Dt:	06/10/1997	Application #:	08465384	Filing Dt:	06/05/1995
Title:	METHOD OF DETECTING SUB-PPB LEVELS OF OLIGONUCLEOTIDES IN BIOLOGICAL FLUIDS

Patent #:	5856459	Issue Dt:	01/05/1999	Application #:	08468352	Filing Dt:	06/06/1995
Title:	OLIGONUCLEOTIDES SPECIFIC FOR HEPATITIS B VIRUS

Patent #:	6509149	Issue Dt:	01/21/2003	Application #:	08471974	Filing Dt:	06/06/1995
Publication #:	US20020068820	Pub Dt:	06/06/2002
Title:	HPV-SPECIFIC OLIGONUCLEOTIDES

Patent #:	5679555	Issue Dt:	10/21/1997	Application #:	08478940	Filing Dt:	06/07/1995
Title:	METHOD OF USING RIBOZYME ANALOGS HAVING RIGID, NON-NUCLEOTIDIC MOLECULAR LINKERS

Patent #:	5605890	Issue Dt:	02/25/1997	Application #:	08480833	Filing Dt:	06/07/1995
Title:	CYCLODEXTRIN CELLULAR DELIVERY SYSTEM FOR OLIGONUCLEOTIDES

Patent #:	5616565	Issue Dt:	04/01/1997	Application #:	08480834	Filing Dt:	06/07/1995
Title:	CYCLODEXTRIN CELLULAR DELIVERY SYSTEM FOR OLIGONUCLEOTIDES

Patent #:	5919772	Issue Dt:	07/06/1999	Application #:	08481876	Filing Dt:	06/07/1995
Title:	ANTISENSE OLIGONUCLEOTIDES HAVING TUMORIGENICITY-INHIBITING ACTIVITY

Patent #:	5668262	Issue Dt:	09/16/1997	Application #:	08485112	Filing Dt:	06/07/1995
Title:	METHOD OF TRITIUM LABELING OLIGONUCLEOTIDES

Patent #:	5801156	Issue Dt:	09/01/1998	Application #:	08501626	Filing Dt:	07/12/1995
Title:	INHIBITION OF NEOVASCULARIZATION USING VEGF-SPECIFIC OLIGONUCLEOTIDES

Patent #:	5661135	Issue Dt:	08/26/1997	Application #:	08501779	Filing Dt:	07/13/1995
Title:	HUMAN VEGF-SPECIFIC OLIGONUCLEOTIDES

Patent #:	5639736	Issue Dt:	06/17/1997	Application #:	08502185	Filing Dt:	07/13/1995
Title:	HUMAN VEGF-SPECIFIC OLIGONUCLEOTIDES

Patent #:	5968909	Issue Dt:	10/19/1999	Application #:	08511536	Filing Dt:	08/04/1995
Title:	METHOD OF MODULATING GENE EXPRESSION WITH REDUCED IMMUNOSTIMULATORY RESPONSE

Patent #:	5652356	Issue Dt:	07/29/1997	Application #:	08516454	Filing Dt:	08/17/1995
Title:	INVERTED CHIMERIC AND HYBRID OLIGONUCLEOTIDES

Patent #:	5614622	Issue Dt:	03/25/1997	Application #:	08518921	Filing Dt:	08/24/1995
Title:	THE 4-PENTENOYL MOIETY AS A NUCLEOSIDE-AMINO PROTECTING GROUP, PENTENOYL-PROTECTED NUCLEOTIDE SYNTHONS, AND RELATED OLIGONUCLEOTIDE SYNTHESES

Patent #:	6140482	Issue Dt:	10/31/2000	Application #:	08519318	Filing Dt:	08/25/1995
Title:	PRIMARY PHOSPHORAMIDATE INTERNUCLEOSIDE LINKAGES AND OLIGONUCLEOTIDES CONTAINING THE SAME

Patent #:	6667293	Issue Dt:	12/23/2003	Application #:	08527126	Filing Dt:	09/12/1995
Title:	USE OF CYCLODEXTRINS TO MODULATE GENE EXPRESSION WITH REDUCED IMMUNOSTIMULATORY RESPONSE

Patent #:	5969117	Issue Dt:	10/19/1999	Application #:	08532979	Filing Dt:	09/22/1995
Title:	MODIFIED PROTEIN KINASE A-SPECIFIC OLIGONUCLEOTIDE

Patent #:	5705629	Issue Dt:	01/06/1998	Application #:	08546318	Filing Dt:	10/20/1995
Title:	METHODS FOR H-PHOSPHONATE SYNTHESIS OF MONO- AND OLIGONUCLEOTIDES

Patent #:	5641756	Issue Dt:	06/24/1997	Application #:	08569926	Filing Dt:	12/08/1995
Title:	MODIFIED VEGF OLIGONUCLEOTIDES

Patent #:	5955599	Issue Dt:	09/21/1999	Application #:	08570390	Filing Dt:	12/11/1995
Title:	O- AND S-METHYLPHOSPHOTRIESTER INTERNUCLEOSIDE LINKAGES AND OLIGONUCLEOTIDES CONTAINING THE SAME

Patent #:	6531589	Issue Dt:	03/11/2003	Application #:	08598320	Filing Dt:	02/08/1996
Title:	BASE PROTECTING GROUPS AND SYNTHONS FOR OLIGONUCLEOTIDE SYNTHESIS

Patent #:	5962674	Issue Dt:	10/05/1999	Application #:	08606915	Filing Dt:	02/26/1996
Title:	SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING ALKYLPHOSPHONATE INTERNUCLEOSIDE LINKAGES

Patent #:	5807525	Issue Dt:	09/15/1998	Application #:	08608702	Filing Dt:	02/29/1996
Title:	APPARATUS AND PROCESS FOR MULTI STAGE SOLID PHASE SYNTHESIS OF LONG CHAINED ORGANIC MOLECULES

Patent #:	6340749	Issue Dt:	01/22/2002	Application #:	08647354	Filing Dt:	05/09/1996
Title:	IN SITU PREPARATION OF NUCLEOSIDE PHOSPHORAMIDITES AND OLIGONUCLEOTIDE SYNTHESIS

Patent #:	6489464	Issue Dt:	12/03/2002	Application #:	08664786	Filing Dt:	06/17/1996
Title:	BRANCHED OLIGONUCLEOTIDES AS PATHOGEN-INHIBITORY AGENTS

Patent #:	5856462	Issue Dt:	01/05/1999	Application #:	08711568	Filing Dt:	09/10/1996
Title:	OLIGONUCLEOTIDES HAVING MODIFIED CPG DINUCLEOSIDES

Patent #:	5886165	Issue Dt:	03/23/1999	Application #:	08719970	Filing Dt:	09/24/1996
Title:	MIXED BACKBONE ANTISENSE OLIGONUCLEOTIDES CONTAINING 2'-5'- RIBONUCLEOTIDE- AND 3'-5'-DEOXYRIBONUCLEOTIDES SEGMENTS

Patent #:	6306829	Issue Dt:	10/23/2001	Application #:	08761708	Filing Dt:	12/06/1996
Title:	MODIFIED VEGF OLIGONUCLEOTIDES FOR TREATMENT OF SKIN DISORDERS

Patent #:	6087491	Issue Dt:	07/11/2000	Application #:	08827561	Filing Dt:	05/02/1997
Title:	EXTREMELY HIGH PURITY OLIGONUCLEOTIDES AND METHODS OF SYNTHESIZING THEM USING DIMER BLOCKS

Patent #:	5739314	Issue Dt:	04/14/1998	Application #:	08846124	Filing Dt:	04/25/1997
Title:	METHOD FOR SYNTHESIZING 2'-O-SUBSTITUTED PYRIMIDINE NUCLEOSIDES

Patent #:	6509459	Issue Dt:	01/21/2003	Application #:	08846303	Filing Dt:	04/30/1997
Title:	NOVEL BASE PROTECTING GROUPS AND RAPID PROCESS FOR OLIGONUCLEOTIDE SYNTHESIS

Patent #:	6489304	Issue Dt:	12/03/2002	Application #:	08846879	Filing Dt:	05/01/1997
Publication #:	US20010006945	Pub Dt:	07/05/2001
Title:	HYPERSTRUCTURE-FORMING CARRIERS

Patent #:	6426334	Issue Dt:	07/30/2002	Application #:	08848229	Filing Dt:	04/30/1997
Title:	OLIGONUCLEOTIDE MEDIATED SPECIFIC CYTOKINE INDUCTION AND REDUCTION OF TUMOR GROWTH IN A MAMMAL

Patent #:	6096881	Issue Dt:	08/01/2000	Application #:	08865666	Filing Dt:	05/30/1997
Title:	NOVEL SULFUR TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS

Patent #:	5973136	Issue Dt:	10/26/1999	Application #:	08886670	Filing Dt:	07/01/1997
Title:	INVERTED CHIMERIC OLIGONUCLEOTIDES

Patent #:	5773601	Issue Dt:	06/30/1998	Application #:	08886860	Filing Dt:	07/01/1997
Title:	INVERTED CHIMERIC AND HYBRID OLIGONUCLEOTIDES

Patent #:	6458940	Issue Dt:	10/01/2002	Application #:	08887497	Filing Dt:	07/02/1997
Publication #:	US20010010899	Pub Dt:	08/02/2001
Title:	HPV-SPECIFIC OLIGONUCLEOTIDES

Patent #:	NONE	Issue Dt:		Application #:	08887505	Filing Dt:	07/02/1997
Publication #:	US20020081577	Pub Dt:	06/27/2002
Title:	OLIGONUCLEOTIDES SPECIIFIC FOR HEPATITIS C VIRUS

Patent #:	6500944	Issue Dt:	12/31/2002	Application #:	08895136	Filing Dt:	07/16/1997
Publication #:	US20020010326	Pub Dt:	01/24/2002
Title:	NOVEL SULFURIZING REAGENT: 3-ARYL-1,2,4-DITHIAZOLINE-5-ONES

Patent #:	6984729	Issue Dt:	01/10/2006	Application #:	08901612	Filing Dt:	07/28/1997
Title:	OLIGONUCLEOTIDES SPECIFIC FOR HEPATITIS B VIRUS

Patent #:	6117992	Issue Dt:	09/12/2000	Application #:	08920087	Filing Dt:	08/26/1997
Title:	IMPROVED REAGENTS AND PROCESS FOR SYNTHESIS OF OLIGONUCLEOSIDE CONTAINING PHOSPHORODITHIOATE INTERNUCLEOSIDE

Assignor

HYBRIDON, INC.

Exec Dt:

01/16/1998

Assignee

SILICON VALLEY BANK

40 WILLIAMS STREET

CAMBRIDGE, MASSACHUSETTS 02139

Correspondence name and address
	WOLF, GREENFIELD & SACKS, P.C.
	STANLEY SACKS, ESQ.
	FEDERAL RESERVE PLAZA
	600 ATLANTIC AVENUE
	BOSTON, MA 02210

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