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Reel/Frame:	018109/0041			Pages:	18
		Recorded:	08/15/2006
Attorney Dkt #:	121647-01046
Conveyance:	SECURITY AGREEMENT

Total properties: 41

Patent #:	5292756	Issue Dt:	03/08/1994	Application #:	07860747	Filing Dt:	03/25/1992
Title:	NOVEL SULFONAMIDE FIBRINOGEN RECEPTOR ANTAGONISTS

Patent #:	5658929	Issue Dt:	08/19/1997	Application #:	08505417	Filing Dt:	07/21/1995
Title:	NOVEL SULFONAMIDE FIBRINOGEN RECEPTOR ANTAGONISTS

Patent #:	5733919	Issue Dt:	03/31/1998	Application #:	08735878	Filing Dt:	10/23/1996
Title:	COMPOSITIONS FOR INHIBITING PLATELET AGGREGATION

Patent #:	5814643	Issue Dt:	09/29/1998	Application #:	08861545	Filing Dt:	05/22/1997
Title:	NOVEL SULFONAMIDE FIBRINOGEN RECEPTOR ANTAGONISTS

Patent #:	5978698	Issue Dt:	11/02/1999	Application #:	08943872	Filing Dt:	10/08/1997
Title:	ANGIOPLASTY PROCEDURE USING NONIONIC CONTRAST MEDIA

Patent #:	5972967	Issue Dt:	10/26/1999	Application #:	08965922	Filing Dt:	11/07/1997
Title:	COMPOSITIONS FOR INHIBITING PLATELET AGGREGATION

Patent #:	5965581	Issue Dt:	10/12/1999	Application #:	09079776	Filing Dt:	05/15/1998
Title:	COMPOSITIONS FOR INHIBITING PLATELET AGGREGATION

Patent #:	5880136	Issue Dt:	03/09/1999	Application #:	09130334	Filing Dt:	08/06/1998
Title:	NOVEL SULFONAMIDE FIBRINOGEN RECEPTOR ANTAGONISTS

Patent #:	6040317	Issue Dt:	03/21/2000	Application #:	09221044	Filing Dt:	12/28/1998
Title:	NOVEL SULFONAMIDE FIBRINOGEN RECEPTOR ANTAGONISTS

Patent #:	6136794	Issue Dt:	10/24/2000	Application #:	09240429	Filing Dt:	01/29/1999
Title:	PLATELET AGGREGATION INHIBITION USING LOW MOLECULAR WEIGHT HEPARIN IN COMBINATION WITH A GP IIB/IIIA ANTAGONIST

Patent #:	6677356	Issue Dt:	01/13/2004	Application #:	09645237	Filing Dt:	08/24/2000
Title:	TREATMENT OF CARDIOVASCULAR AND RELATED PATHOLOGIES

Patent #:	6605612	Issue Dt:	08/12/2003	Application #:	09795689	Filing Dt:	02/28/2001
Publication #:	US20020010158	Pub Dt:	01/24/2002
Title:	CARDIOPROTECTIVE PHOSPHONATES AND MALONATES

Patent #:	6586414	Issue Dt:	07/01/2003	Application #:	09820199	Filing Dt:	03/28/2001
Publication #:	US20010056081	Pub Dt:	12/27/2001
Title:	TREATMENT OF CEREBROVASCULAR DISEASE

Patent #:	6417204	Issue Dt:	07/09/2002	Application #:	09900718	Filing Dt:	07/06/2001
Title:	PYRIDOXINE AND PYRIDOXAL ANALOGUES: CARDIOVASCULAR THERAPEUTICS

Patent #:	6548519	Issue Dt:	04/15/2003	Application #:	10147263	Filing Dt:	05/15/2002
Title:	PYRIDOXINE AND PYRIDOXAL ANALOGUES: NOVEL USES

Patent #:	6861439	Issue Dt:	03/01/2005	Application #:	10254197	Filing Dt:	09/24/2002
Publication #:	US20030114424	Pub Dt:	06/19/2003
Title:	TREATMENT OF CEREBROVASCULAR DISEASE

Patent #:	7105673	Issue Dt:	09/12/2006	Application #:	10282325	Filing Dt:	10/28/2002
Publication #:	US20030114677	Pub Dt:	06/19/2003
Title:	CARDIOPROTECTIVE PHOSPHONATES AND MALONATES

Patent #:	6667315	Issue Dt:	12/23/2003	Application #:	10282326	Filing Dt:	10/28/2002
Publication #:	US20030114678	Pub Dt:	06/19/2003
Title:	CARDIOPROTECTIVE PHOSPHONATES AND MALONATES

Patent #:	6780997	Issue Dt:	08/24/2004	Application #:	10282328	Filing Dt:	10/28/2002
Publication #:	US20030120074	Pub Dt:	06/26/2003
Title:	CARDIOPROTECTIVE PHOSPHONATES AND MALONATES

Patent #:	6867215	Issue Dt:	03/15/2005	Application #:	10377507	Filing Dt:	02/28/2003
Publication #:	US20030181422	Pub Dt:	09/25/2003
Title:	CARDIOPROTECTIVE PHOSPHONATES AND MALONATES

Patent #:	6897228	Issue Dt:	05/24/2005	Application #:	10411552	Filing Dt:	04/10/2003
Publication #:	US20040010015	Pub Dt:	01/15/2004
Title:	PYRIDOXINE AND PYRIDOXAL ANALOGUES: NEW USES

Patent #:	6770660	Issue Dt:	08/03/2004	Application #:	10427436	Filing Dt:	05/01/2003
Publication #:	US20030207918	Pub Dt:	11/06/2003
Title:	METHOD FOR INHIBITING PLATELET AGGREGATION

Patent #:	NONE	Issue Dt:		Application #:	10549505	Filing Dt:	06/27/2006
Publication #:	US20060241083	Pub Dt:	10/26/2006
Title:	Heteroaryl phosphonates, compositions containing them and methods of treatment of various disorders using them

Patent #:	7132430	Issue Dt:	11/07/2006	Application #:	10639876	Filing Dt:	08/12/2003
Publication #:	US20040033989	Pub Dt:	02/19/2004
Title:	TREATMENT OF CARDIOVASCULAR AND RELATED PATHOLOGIES

Patent #:	7144892	Issue Dt:	12/05/2006	Application #:	10639877	Filing Dt:	08/12/2003
Publication #:	US20040033990	Pub Dt:	02/19/2004
Title:	TREATMENT OF CARDIOVASCULAR AND RELATED PATHOLOGIES

Patent #:	7148233	Issue Dt:	12/12/2006	Application #:	10639948	Filing Dt:	08/12/2003
Publication #:	US20040038945	Pub Dt:	02/26/2004
Title:	TREATMENT OF CARDIOVASCULAR AND RELATED PATHOLOGIES

Patent #:	7125889	Issue Dt:	10/24/2006	Application #:	10639949	Filing Dt:	08/12/2003
Publication #:	US20040033991	Pub Dt:	02/19/2004
Title:	TREATING OF CARDIOVASCULAR AND RELATED PATHOLOGIES

Patent #:	7115625	Issue Dt:	10/03/2006	Application #:	10639950	Filing Dt:	08/12/2003
Publication #:	US20040033992	Pub Dt:	02/19/2004
Title:	TREATMENT OF CARDIOVASCULAR AND RELATED PATHOLOGIES

Patent #:	7115626	Issue Dt:	10/03/2006	Application #:	10639955	Filing Dt:	08/12/2003
Publication #:	US20040033993	Pub Dt:	02/19/2004
Title:	TREATMENT OF CARDIOVASCULAR AND RELATED PATHOLOGIES

Patent #:	NONE	Issue Dt:		Application #:	10729276	Filing Dt:	12/03/2003
Publication #:	US20040121988	Pub Dt:	06/24/2004
Title:	Treatment of cerebrovascular disease

Patent #:	7442689	Issue Dt:	10/28/2008	Application #:	10732037	Filing Dt:	12/09/2003
Publication #:	US20040171588	Pub Dt:	09/02/2004
Title:	CARDIOPROTECTIVE PHOSPHONATES AND MALONATES

Patent #:	NONE	Issue Dt:		Application #:	10909608	Filing Dt:	08/02/2004
Publication #:	US20050004231	Pub Dt:	01/06/2005
Title:	Method for inhibiting platelet aggregation

Patent #:	7459468	Issue Dt:	12/02/2008	Application #:	10974707	Filing Dt:	10/28/2004
Publication #:	US20060094748	Pub Dt:	05/04/2006
Title:	ARYL SULFONIC PYRIDOXINES AS ANTIPLATELET AGENTS

Patent #:	NONE	Issue Dt:		Application #:	10974718	Filing Dt:	10/28/2004
Publication #:	US20060094749	Pub Dt:	05/04/2006
Title:	Substituted pyridoxines as anti-platelet agents

Patent #:	7425570	Issue Dt:	09/16/2008	Application #:	11016737	Filing Dt:	12/21/2004
Publication #:	US20050107443	Pub Dt:	05/19/2005
Title:	PYRIDOXINE AND PYRIDOXAL ANALOGUES: NEW USES

Patent #:	NONE	Issue Dt:		Application #:	11177248	Filing Dt:	07/07/2005
Publication #:	US20060019929	Pub Dt:	01/26/2006
Title:	Combination therapies employing platelet aggregation drugs

Patent #:	NONE	Issue Dt:		Application #:	11202272	Filing Dt:	08/10/2005
Publication #:	US20060035864	Pub Dt:	02/16/2006
Title:	Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders

Patent #:	7812037	Issue Dt:	10/12/2010	Application #:	11262509	Filing Dt:	10/28/2005
Publication #:	US20060094761	Pub Dt:	05/04/2006
Title:	DUAL ANTIPLATELET/ANTICOAGULANT PYRIDOXINE ANALOGS

Patent #:	NONE	Issue Dt:		Application #:	11288971	Filing Dt:	11/28/2005
Publication #:	US20070243249	Pub Dt:	10/18/2007
Title:	Novel formulation of pyridoxal-5'-phosphate and method of preparation

Patent #:	7375112	Issue Dt:	05/20/2008	Application #:	11326201	Filing Dt:	01/05/2006
Publication #:	US20060148763	Pub Dt:	07/06/2006
Title:	COMPOUNDS AND METHODS FOR REGULATING TRIGLYCERIDE LEVELS

Patent #:	NONE	Issue Dt:		Application #:	11424069	Filing Dt:	06/14/2006
Publication #:	US20070060549	Pub Dt:	03/15/2007
Title:	COMBINATION THERAPIES EMPLOYING ACE INHIBITORS AND USES THEREOF FOR THE TREATMENT OF DIABETIC DISORDERS

Assignor

MEDICURE INTERNATIONAL INC.

Exec Dt:

08/11/2006

Assignee

MERRILL LYNCH CAPITAL CANADA INC.

181 BAY STREET

SUITE 400

TORONTO, ONTARIO, CANADA M5J2V8

Correspondence name and address
	DAVID M. PERRY
	ONE LOGAN SQUARE
	9TH FLOOR
	PHILADELPHIA, PA 19103-6998

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