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Reel/Frame:	052795/0074			Pages:	42
		Recorded:	05/29/2020
Attorney Dkt #:	054809-0065
Conveyance:	INTELLECTUAL PROPERTY SECURITY AGREEMENT

Total properties: 56

Patent #:	8598186	Issue Dt:	12/03/2013	Application #:	13869520	Filing Dt:	04/24/2013
Publication #:	US20130237544	Pub Dt:	09/12/2013
Title:	CDK INHIBITORS

Patent #:	8598197	Issue Dt:	12/03/2013	Application #:	13869576	Filing Dt:	04/24/2013
Publication #:	US20130237533	Pub Dt:	09/12/2013
Title:	CDK INHIBITORS

Patent #:	8691830	Issue Dt:	04/08/2014	Application #:	13869594	Filing Dt:	04/24/2013
Publication #:	US20130237534	Pub Dt:	09/12/2013
Title:	CDK INHIBITORS

Patent #:	9808461	Issue Dt:	11/07/2017	Application #:	13988158	Filing Dt:	07/31/2013
Publication #:	US20130303543	Pub Dt:	11/14/2013
Title:	PROTECTION OF RENAL TISSUES FROM ISCHEMIA THROUGH INHIBITION OF THE PROLIFERATIVE KINASES CDK4 AND CDK6

Patent #:	8829012	Issue Dt:	09/09/2014	Application #:	14162637	Filing Dt:	01/23/2014
Publication #:	US20140142306	Pub Dt:	05/22/2014
Title:	CDK INHIBITORS

Patent #:	8822683	Issue Dt:	09/02/2014	Application #:	14162649	Filing Dt:	01/23/2014
Publication #:	US20140142299	Pub Dt:	05/22/2014
Title:	CDK INHIBITORS

Patent #:	9487530	Issue Dt:	11/08/2016	Application #:	14212430	Filing Dt:	03/14/2014
Publication #:	US20140275066	Pub Dt:	09/18/2014
Title:	Transient Protection of Normal Cells During Chemotherapy

Patent #:	9464092	Issue Dt:	10/11/2016	Application #:	14212911	Filing Dt:	03/14/2014
Publication #:	US20140275067	Pub Dt:	09/18/2014
Title:	Transient Protection of Normal Cells During Chemotherapy

Patent #:	9527857	Issue Dt:	12/27/2016	Application #:	14214048	Filing Dt:	03/14/2014
Publication #:	US20140271466	Pub Dt:	09/18/2014
Title:	HSPC-Sparing Treatments for RB-Positive Abnormal Cellular Proliferation

Patent #:	10202392	Issue Dt:	02/12/2019	Application #:	14396759	Filing Dt:	10/24/2014
Publication #:	US20150087831	Pub Dt:	03/26/2015
Title:	SYNTHESIS OF LACTAMS

Patent #:	9102682	Issue Dt:	08/11/2015	Application #:	14452296	Filing Dt:	08/05/2014
Publication #:	US20150031880	Pub Dt:	01/29/2015
Title:	CDK Inhibitors

Patent #:	9260442	Issue Dt:	02/16/2016	Application #:	14498796	Filing Dt:	09/26/2014
Publication #:	US20150018348	Pub Dt:	01/15/2015
Title:	LACTAM KINASE INHIBITORS

Patent #:	9717735	Issue Dt:	08/01/2017	Application #:	14690180	Filing Dt:	04/17/2015
Publication #:	US20150299212	Pub Dt:	10/22/2015
Title:	Tricyclic Lactams for Use in HSPC-Sparing Treatments for RB-Positive Abnormal Cellular Proliferation

Patent #:	9499564	Issue Dt:	11/22/2016	Application #:	14712582	Filing Dt:	05/14/2015
Publication #:	US20150246925	Pub Dt:	09/03/2015
Title:	CDK Inhibitors

Patent #:	9481691	Issue Dt:	11/01/2016	Application #:	14712630	Filing Dt:	05/14/2015
Publication #:	US20150246926	Pub Dt:	09/03/2015
Title:	CDK Inhibitors

Patent #:	9745316	Issue Dt:	08/29/2017	Application #:	14982443	Filing Dt:	12/29/2015
Publication #:	US20160108054	Pub Dt:	04/21/2016
Title:	Lactam Kinase Inhibitors

Patent #:	9931345	Issue Dt:	04/03/2018	Application #:	15288878	Filing Dt:	10/07/2016
Publication #:	US20170037051	Pub Dt:	02/09/2017
Title:	TRANSIENT PROTECTION OF NORMAL CELLS DURING CHEMOTHERAPY

Patent #:	10085992	Issue Dt:	10/02/2018	Application #:	15342990	Filing Dt:	11/03/2016
Publication #:	US20170065597	Pub Dt:	03/09/2017
Title:	Transient Protection of Normal Cells During Chemotherapy

Patent #:	9957276	Issue Dt:	05/01/2018	Application #:	15348770	Filing Dt:	11/10/2016
Publication #:	US20170057971	Pub Dt:	03/02/2017
Title:	CDK Inhibitors

Patent #:	9856268	Issue Dt:	01/02/2018	Application #:	15348862	Filing Dt:	11/10/2016
Publication #:	US20170057972	Pub Dt:	03/02/2017
Title:	LACTAM KINASE INHIBITORS

Patent #:	10118910	Issue Dt:	11/06/2018	Application #:	15374966	Filing Dt:	12/09/2016
Publication #:	US20170166550	Pub Dt:	06/15/2017
Title:	BENZOTHIOPHENE-BASED SELECTIVE ESTROGEN RECEPTOR DOWNREGULATORS

Patent #:	10076523	Issue Dt:	09/18/2018	Application #:	15387083	Filing Dt:	12/21/2016
Publication #:	US20170100405	Pub Dt:	04/13/2017
Title:	HSPC-Sparing Treatments for RB-Positive Abnormal Cellular Proliferation

Patent #:	10231969	Issue Dt:	03/19/2019	Application #:	15457699	Filing Dt:	03/13/2017
Publication #:	US20170182043	Pub Dt:	06/29/2017
Title:	ANTI-NEOPLASTIC COMBINATIONS AND DOSING REGIMENS USING CDK4/6 INHIBITOR COMPOUNDS TO TREAT RB-POSITIVE TUMORS

Patent #:	10376519	Issue Dt:	08/13/2019	Application #:	15665071	Filing Dt:	07/31/2017
Publication #:	US20170333440	Pub Dt:	11/23/2017
Title:	TRICYCLIC LACTAMS FOR USE IN HSPC-SPARING TREATMENTS FOR RB-POSITIVE ABNORMAL CELLULAR PROLIFERATION

Patent #:	10464940	Issue Dt:	11/05/2019	Application #:	15860483	Filing Dt:	01/02/2018
Publication #:	US20180127431	Pub Dt:	05/10/2018
Title:	LACTAM KINASE INHIBITORS

Patent #:	10208011	Issue Dt:	02/19/2019	Application #:	15893295	Filing Dt:	02/09/2018
Publication #:	US20180230123	Pub Dt:	08/16/2018
Title:	BENZOTHIOPHENE ESTROGEN RECEPTOR MODULATORS

Patent #:	10189849	Issue Dt:	01/29/2019	Application #:	15918834	Filing Dt:	03/12/2018
Publication #:	US20180201617	Pub Dt:	07/19/2018
Title:	CDK Inhibitors

Patent #:	10189850	Issue Dt:	01/29/2019	Application #:	15918852	Filing Dt:	03/12/2018
Publication #:	US20180201618	Pub Dt:	07/19/2018
Title:	CDK INHIBITORS

Patent #:	10189851	Issue Dt:	01/29/2019	Application #:	15918877	Filing Dt:	03/12/2018
Publication #:	US20180201619	Pub Dt:	07/19/2018
Title:	CDK INHIBITORS

Patent #:	10660896	Issue Dt:	05/26/2020	Application #:	15943278	Filing Dt:	04/02/2018
Publication #:	US20180221378	Pub Dt:	08/09/2018
Title:	TRANSIENT PROTECTION OF NORMAL CELLS DURING CHEMOTHERAPY

Patent #:	10966984	Issue Dt:	04/06/2021	Application #:	16112360	Filing Dt:	08/24/2018
Publication #:	US20180360840	Pub Dt:	12/20/2018
Title:	TRANSIENT PROTECTION OF NORMAL CELLS DURING CHEMOTHERAPY

Patent #:	10434104	Issue Dt:	10/08/2019	Application #:	16112362	Filing Dt:	08/24/2018
Publication #:	US20180360841	Pub Dt:	12/20/2018
Title:	HSPC-SPARING TREATMENTS FOR RB-POSITIVE ABNORMAL CELLULAR PROLIFERATION

Patent #:	10413547	Issue Dt:	09/17/2019	Application #:	16142574	Filing Dt:	09/26/2018
Publication #:	US20190030034	Pub Dt:	01/31/2019
Title:	TREATMENT OF RB-NEGATIVE TUMORS USING TOPOISOMERASE INHIBITORS IN COMBINATION WITH CYCLIN DEPENDENT KINASE 4/6 INHIBITORS

Patent #:	10413547	Issue Dt:	09/17/2019	Application #:	16142574	Filing Dt:	09/26/2018
Publication #:	US20190030034	Pub Dt:	01/31/2019
Title:	TREATMENT OF RB-NEGATIVE TUMORS USING TOPOISOMERASE INHIBITORS IN COMBINATION WITH CYCLIN DEPENDENT KINASE 4/6 INHIBITORS

Patent #:	10377735	Issue Dt:	08/13/2019	Application #:	16169812	Filing Dt:	10/24/2018
Publication #:	US20190055209	Pub Dt:	02/21/2019
Title:	BENZOTHIOPHENE-BASED SELECTIVE ESTROGEN RECEPTOR DOWNREGULATORS

Patent #:	10925878	Issue Dt:	02/23/2021	Application #:	16178419	Filing Dt:	11/01/2018
Publication #:	US20190070185	Pub Dt:	03/07/2019
Title:	HSPC-SPARING TREATMENTS FOR RB-POSITIVE ABNORMAL CELLULAR PROLIFERATION

Patent #:	10633362	Issue Dt:	04/28/2020	Application #:	16221201	Filing Dt:	12/14/2018
Publication #:	US20190119243	Pub Dt:	04/25/2019
Title:	BENZOTHIOPHENE ESTROGEN RECEPTOR MODULATORS

Patent #:	10696682	Issue Dt:	06/30/2020	Application #:	16226430	Filing Dt:	12/19/2018
Publication #:	US20190119292	Pub Dt:	04/25/2019
Title:	CDK INHIBITORS

Patent #:	10981922	Issue Dt:	04/20/2021	Application #:	16227456	Filing Dt:	12/20/2018
Publication #:	US20190119293	Pub Dt:	04/25/2019
Title:	Synthesis of Lactams

Patent #:	10709711	Issue Dt:	07/14/2020	Application #:	16228308	Filing Dt:	12/20/2018
Publication #:	US20190125752	Pub Dt:	05/02/2019
Title:	Highly Active Anti-Neoplastic and Anti-Proliferative Agents

Patent #:	10865210	Issue Dt:	12/15/2020	Application #:	16230381	Filing Dt:	12/21/2018
Publication #:	US20190135820	Pub Dt:	05/09/2019
Title:	SYNTHESIS OF N-(HETEROARYL)-PYRROLO[3,2-D]PYRIMIDIN-2-AMINES

Patent #:	10654831	Issue Dt:	05/19/2020	Application #:	16230388	Filing Dt:	12/21/2018
Publication #:	US20190135784	Pub Dt:	05/09/2019
Title:	ANTIPROLIFERATIVE PYRIMIDINE-BASED COMPOUNDS

Patent #:	10829490	Issue Dt:	11/10/2020	Application #:	16230396	Filing Dt:	12/21/2018
Publication #:	US20190135811	Pub Dt:	05/09/2019
Title:	SUBSTITUTED DIHYDROPYRAZINO[1',2':1,5]PYRROLO[2,3-d]PYRIMIDINE-BASED ANTIPROLIFERATIVE AGENTS

Patent #:	10618905	Issue Dt:	04/14/2020	Application #:	16230412	Filing Dt:	12/21/2018
Publication #:	US20190119294	Pub Dt:	04/25/2019
Title:	PYRIMIDINE-BASED COMPOUNDS FOR THE TREATMENT OF CANCER

Patent #:	11446295	Issue Dt:	09/20/2022	Application #:	16254364	Filing Dt:	01/22/2019
Publication #:	US20190151311	Pub Dt:	05/23/2019
Title:	ANTI-NEOPLASTIC COMBINATIONS AND DOSING REGIMENS USING CDK4/6 INHIBITOR COMPOUNDS TO TREAT RB-POSITIVE TUMORS

Patent #:	NONE	Issue Dt:		Application #:	16268317	Filing Dt:	02/05/2019
Publication #:	US20190167691	Pub Dt:	06/06/2019
Title:	TRANSIENT PROTECTION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS AGAINST IONIZING RADIATION

Patent #:	10703747	Issue Dt:	07/07/2020	Application #:	16393258	Filing Dt:	04/24/2019
Publication #:	US20190248780	Pub Dt:	08/15/2019
Title:	BENZOTHIOPHENE-BASED SELECTIVE MIXED ESTROGEN RECEPTOR DOWNREGULATORS

Patent #:	11072595	Issue Dt:	07/27/2021	Application #:	16424240	Filing Dt:	05/28/2019
Publication #:	US20200123126	Pub Dt:	04/23/2020
Title:	BENZOTHIOPHENE-BASED SELECTIVE ESTROGEN RECEPTOR DOWNREGULATOR COMPOUNDS

Patent #:	11529352	Issue Dt:	12/20/2022	Application #:	16432244	Filing Dt:	06/05/2019
Publication #:	US20190321370	Pub Dt:	10/24/2019
Title:	PRESERVATION OF IMMUNE RESPONSE DURING CHEMOTHERAPY REGIMENS

Patent #:	11364222	Issue Dt:	06/21/2022	Application #:	16460502	Filing Dt:	07/02/2019
Publication #:	US20190321332	Pub Dt:	10/24/2019
Title:	COMBINATION THERAPY FOR TREATMENT OF CANCER

Patent #:	10807964	Issue Dt:	10/20/2020	Application #:	16537079	Filing Dt:	08/09/2019
Publication #:	US20200079752	Pub Dt:	03/12/2020
Title:	BENZOTHIOPHENE-BASED SELECTIVE ESTROGEN RECEPTOR DOWNREGULATORS

Patent #:	11395821	Issue Dt:	07/26/2022	Application #:	16547342	Filing Dt:	08/21/2019
Publication #:	US20190374545	Pub Dt:	12/12/2019
Title:	TREATMENT OF EGFR-DRIVEN CANCER WITH FEWER SIDE EFFECTS

Patent #:	11090306	Issue Dt:	08/17/2021	Application #:	16572418	Filing Dt:	09/16/2019
Publication #:	US20200022983	Pub Dt:	01/23/2020
Title:	TREATMENT OF RB-NEGATIVE TUMORS USING TOPOISOMERASE INHIBITORS IN COMBINATION WITH CYCLIN DEPENDENT KINASE 4/6 INHIBITORS

Patent #:	11261193	Issue Dt:	03/01/2022	Application #:	16721631	Filing Dt:	12/19/2019
Publication #:	US20200123168	Pub Dt:	04/23/2020
Title:	MORPHIC FORMS OF G1T38 AND METHODS OF MANUFACTURE THEREOF

Patent #:	10981887	Issue Dt:	04/20/2021	Application #:	16824290	Filing Dt:	03/19/2020
Publication #:	US20200216406	Pub Dt:	07/09/2020
Title:	BENZOTHIOPHENE ESTROGEN RECEPTOR MODULATORS

Patent #:	NONE	Issue Dt:		Application #:	16847426	Filing Dt:	04/13/2020
Publication #:	US20200239486	Pub Dt:	07/30/2020
Title:	PYRIMIDINE-BASED COMPOUNDS FOR THE TREATMENT OF CANCER

Assignor

G1 THERAPEUTICS, INC.

Exec Dt:

05/29/2020

Assignee

HERCULES CAPITAL, INC., AS COLLATERAL AGENT

400 HAMILTON AVENUE, SUITE 310

PALO ALTO, CALIFORNIA 94301

Correspondence name and address
	LATHAM & WATKINS LLP
	650 TOWN CENTER DRIVE, 20TH FLOOR
	COSTA MESA, CA 92626

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