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Reel/Frame:	070434/0319			Pages:	28
		Recorded:	03/06/2025
Attorney Dkt #:	687747.0065
Conveyance:	AMENDED AND RESTATED PATENT SECURITY AGREEMENT

Total properties: 44

Patent #:	8361490	Issue Dt:	01/29/2013	Application #:	10941942	Filing Dt:	09/16/2004
Publication #:	US20060057208	Pub Dt:	03/16/2006
Title:	BIOCOMPATIBLE DRUG DELIVERY APPARATUS AND METHODS

Patent #:	9066940	Issue Dt:	06/30/2015	Application #:	13147194	Filing Dt:	09/14/2011
Publication #:	US20110319442	Pub Dt:	12/29/2011
Title:	PHARMACEUTICAL COMPOSITIONS COMPRISING IMIDAZOQUINOLIN(AMINES) AND DERIVATIVES THEREOF SUITABLE FOR LOCAL ADMINISTRATION

Patent #:	9040074	Issue Dt:	05/26/2015	Application #:	13553198	Filing Dt:	07/19/2012
Publication #:	US20130046275	Pub Dt:	02/21/2013
Title:	MATERIAL AND METHOD FOR TREATING INTERNAL CAVITIES

Patent #:	9011411	Issue Dt:	04/21/2015	Application #:	13726162	Filing Dt:	12/23/2012
Publication #:	US20130110030	Pub Dt:	05/02/2013
Title:	METHODS FOR TREATMENT OF BLADDER CANCER

Patent #:	8936566	Issue Dt:	01/20/2015	Application #:	13726165	Filing Dt:	12/23/2012
Publication #:	US20130110031	Pub Dt:	05/02/2013
Title:	BIOCOMPATIBLE DRUG DELIVERY APPARATUS AND METHODS

Patent #:	9217160	Issue Dt:	12/22/2015	Application #:	13769025	Filing Dt:	02/15/2013
Publication #:	US20130231267	Pub Dt:	09/05/2013
Title:	ADENOVIRAL ASSEMBLY METHOD

Patent #:	9173936	Issue Dt:	11/03/2015	Application #:	13772235	Filing Dt:	02/20/2013
Publication #:	US20130267481	Pub Dt:	10/10/2013
Title:	PHOSPHOLIPID DRUG ANALOGS

Patent #:	9180183	Issue Dt:	11/10/2015	Application #:	13772253	Filing Dt:	02/20/2013
Publication #:	US20130266635	Pub Dt:	10/10/2013
Title:	PHOSPHOLIPID DRUG ANALOGS

Patent #:	9107919	Issue Dt:	08/18/2015	Application #:	13775906	Filing Dt:	02/25/2013
Publication #:	US20130237561	Pub Dt:	09/12/2013
Title:	PHARMACEUTICAL COMPOSITIONS COMPRISING IMIDAZOQUINOLIN(AMINES) AND DERIVATIVES THEREOF SUITABLE FOR LOCAL ADMINISTRATION

Patent #:	10471150	Issue Dt:	11/12/2019	Application #:	14054731	Filing Dt:	10/15/2013
Publication #:	US20140105884	Pub Dt:	04/17/2014
Title:	MATERIAL AND METHOD FOR TREATING INTERNAL CAVITIES

Patent #:	9801854	Issue Dt:	10/31/2017	Application #:	14600354	Filing Dt:	01/20/2015
Title:	SLOW RELEASE FORMULATIONS OF CELL CYCLE REGULATORS AND ANTI-CANCER AGENTS FOR LOCAL TREATMENT OF SOLID CANCER

Patent #:	9884028	Issue Dt:	02/06/2018	Application #:	14683901	Filing Dt:	04/10/2015
Publication #:	US20150209300	Pub Dt:	07/30/2015
Title:	METHODS FOR TREATMENT OF BLADDER CANCER

Patent #:	10039832	Issue Dt:	08/07/2018	Application #:	14720676	Filing Dt:	05/22/2015
Publication #:	US20150366974	Pub Dt:	12/24/2015
Title:	MATERIAL AND METHOD FOR TREATING INTERNAL CAVITIES

Patent #:	11077156	Issue Dt:	08/03/2021	Application #:	14852981	Filing Dt:	09/14/2015
Publication #:	US20150374766	Pub Dt:	12/31/2015
Title:	ONCOLYTIC ADENOVIRUS COMPOSITIONS

Patent #:	9540407	Issue Dt:	01/10/2017	Application #:	14869677	Filing Dt:	09/29/2015
Publication #:	US20160090395	Pub Dt:	03/31/2016
Title:	PHOSPHOLIPID DRUG ANALOGS

Patent #:	10577589	Issue Dt:	03/03/2020	Application #:	14935866	Filing Dt:	11/09/2015
Publication #:	US20160053235	Pub Dt:	02/25/2016
Title:	ADENOVIRAL ASSEMBLY METHOD

Patent #:	10688049	Issue Dt:	06/23/2020	Application #:	15031519	Filing Dt:	04/22/2016
Publication #:	US20160256391	Pub Dt:	09/08/2016
Title:	PROCESS FOR THE PREPARATION OF A FREEZE-DRIED PHARMACEUTICAL COMPOSITION CONTAINING MITOMYCIN C

Patent #:	10144779	Issue Dt:	12/04/2018	Application #:	15166305	Filing Dt:	05/27/2016
Publication #:	US20160368989	Pub Dt:	12/22/2016
Title:	ANTI-CTLA-4 ANTIBODIES AND METHODS OF USE THEREOF

Patent #:	10994109	Issue Dt:	05/04/2021	Application #:	15322044	Filing Dt:	12/23/2016
Publication #:	US20170136222	Pub Dt:	05/18/2017
Title:	A CONNECTABLE CATHETER

Patent #:	9950069	Issue Dt:	04/24/2018	Application #:	15366256	Filing Dt:	12/01/2016
Publication #:	US20170112935	Pub Dt:	04/27/2017
Title:	MATERIAL AND METHOD FOR TREATING INTERNAL CAVITIES

Patent #:	NONE	Issue Dt:		Application #:	15468565	Filing Dt:	03/24/2017
Publication #:	US20170202893	Pub Dt:	07/20/2017
Title:	ONCOLYTIC TUMOR VIRUSES AND METHODS OF USE

Patent #:	11130968	Issue Dt:	09/28/2021	Application #:	16109513	Filing Dt:	08/22/2018
Publication #:	US20180355374	Pub Dt:	12/13/2018
Title:	HIGH THROUGHPUT ASSAY FOR MEASURING ADENOVIRUS REPLICATION KINETICS

Patent #:	10738325	Issue Dt:	08/11/2020	Application #:	16110207	Filing Dt:	08/23/2018
Publication #:	US20180355379	Pub Dt:	12/13/2018
Title:	EXOGENOUS GENE EXPRESSION IN THERAPEUTIC ADENOVIRUS FOR MINIMAL IMPACT ON VIRAL KINETICS

Patent #:	10479833	Issue Dt:	11/19/2019	Application #:	16165833	Filing Dt:	10/19/2018
Publication #:	US20190135919	Pub Dt:	05/09/2019
Title:	ANTI-CTLA-4 ANTIBODIES AND METHODS OF USE THEREOF

Patent #:	10758482	Issue Dt:	09/01/2020	Application #:	16297839	Filing Dt:	03/11/2019
Publication #:	US20190201334	Pub Dt:	07/04/2019
Title:	IMMUNOMODULATING TREATMENTS OF BODY CAVITIES

Patent #:	11993653	Issue Dt:	05/28/2024	Application #:	16435175	Filing Dt:	06/07/2019
Publication #:	US20200024350	Pub Dt:	01/23/2020
Title:	ANTIBODIES AND METHODS OF USE THEREOF

Patent #:	11267889	Issue Dt:	03/08/2022	Application #:	16858195	Filing Dt:	04/24/2020
Publication #:	US20200354455	Pub Dt:	11/12/2020
Title:	ANTI-CTLA-4 ANTIBODIES AND METHODS OF USE THEREOF

Patent #:	11766405	Issue Dt:	09/26/2023	Application #:	16876505	Filing Dt:	05/18/2020
Publication #:	US20200276128	Pub Dt:	09/03/2020
Title:	PROCESS FOR THE PREPARATION OF A FREEZE-DRIED PHARMACEUTICAL COMPOSITION CONTAINING MITOMYCIN C

Patent #:	11401529	Issue Dt:	08/02/2022	Application #:	16916764	Filing Dt:	06/30/2020
Publication #:	US20200325492	Pub Dt:	10/15/2020
Title:	EXOGENOUS GENE EXPRESSION IN RECOMBINANT ADENOVIRUS FOR MINIMAL IMPACT ON VIRAL KINETICS

Patent #:	NONE	Issue Dt:	07/22/2025	Application #:	17067496	Filing Dt:	10/09/2020
Publication #:	US20210024587	Pub Dt:	01/28/2021
Title:	ONCOLYTIC ADENOVIRUS WITH ENHANCED REPLICATION PROPERTIES COMPRISING MODIFICATIONS IN E1A, E3, AND E4

Patent #:	NONE	Issue Dt:		Application #:	17371546	Filing Dt:	07/09/2021
Publication #:	US20220096577	Pub Dt:	03/31/2022
Title:	ONCOLYTIC ADENOVIRUS COMPOSITIONS

Patent #:	12336979	Issue Dt:	06/24/2025	Application #:	17546204	Filing Dt:	12/09/2021
Publication #:	US20220202773	Pub Dt:	06/30/2022
Title:	MATERIAL AND METHOD FOR TREATING CANCER

Patent #:	NONE	Issue Dt:		Application #:	17582839	Filing Dt:	01/24/2022
Publication #:	US20220267443	Pub Dt:	08/25/2022
Title:	ANTI-CTLA-4 ANTIBODIES AND METHODS OF USE THEREOF

Patent #:	NONE	Issue Dt:		Application #:	17681538	Filing Dt:	02/25/2022
Publication #:	US20220411763	Pub Dt:	12/29/2022
Title:	ADENOVIRAL ASSEMBLY METHOD

Patent #:	11576744	Issue Dt:	02/14/2023	Application #:	17703238	Filing Dt:	03/24/2022
Publication #:	US20220304766	Pub Dt:	09/29/2022
Title:	THERMOSENSITIVE BIO-ADHESIVE HYDROGEL FOR REMOVAL OF URETERAL AND RENAL STONES

Patent #:	12281324	Issue Dt:	04/22/2025	Application #:	17852891	Filing Dt:	06/29/2022
Publication #:	US20230088476	Pub Dt:	03/23/2023
Title:	EXOGENOUS GENE EXPRESSION IN RECOMBINANT ADENOVIRUS FOR MINIMAL IMPACT ON VIRAL KINETICS

Patent #:	NONE	Issue Dt:		Application #:	18129497	Filing Dt:	03/31/2023
Publication #:	US20230241220	Pub Dt:	08/03/2023
Title:	MATERIAL AND METHOD FOR TREATING INTERNAL CAVITIES

Patent #:	NONE	Issue Dt:		Application #:	18180152	Filing Dt:	03/08/2023
Publication #:	US20230218521	Pub Dt:	07/13/2023
Title:	IMMUNOMODULATING TREATMENTS OF BODY CAVITIES

Patent #:	NONE	Issue Dt:		Application #:	18478388	Filing Dt:	09/29/2023
Publication #:	US20240207445	Pub Dt:	06/27/2024
Title:	TUMOR-TARGETING SYNTHETIC ADENOVIRUSES AND USES THEREOF

Patent #:	12171747	Issue Dt:	12/24/2024	Application #:	18535108	Filing Dt:	12/11/2023
Publication #:	US20240108603	Pub Dt:	04/04/2024
Title:	MATERIAL AND METHOD FOR TREATING CANCER

Patent #:	12268745	Issue Dt:	04/08/2025	Application #:	18625862	Filing Dt:	04/03/2024
Publication #:	US20240299550	Pub Dt:	09/12/2024
Title:	MATERIAL AND METHOD FOR TREATING INTERNAL CAVITIES

Patent #:	12263245	Issue Dt:	04/01/2025	Application #:	18665612	Filing Dt:	05/16/2024
Publication #:	US20240382420	Pub Dt:	11/21/2024
Title:	IMMUNOMODULATING TREATMENTS OF BODY CAVITIES

Patent #:	NONE	Issue Dt:		Application #:	18784354	Filing Dt:	07/25/2024
Publication #:	US20250032409	Pub Dt:	01/30/2025
Title:	TREATMENT OF LOW-GRADE INTERMEDIATE-RISK NON-MUSCLE-INVASIVE BLADDER CANCER WITH A THERMALLY GELLING PHARMACEUTICAL COMPOSITION CONTAINING MITOMYCIN

Patent #:	NONE	Issue Dt:		Application #:	18809603	Filing Dt:	08/20/2024
Publication #:	US20250146013	Pub Dt:	05/08/2025
Title:	HIGH THROUGHPUT ASSAY FOR MEASURING ADENOVIRUS REPLICATION KINETICS

Assignor

UROGEN PHARMA LTD.

Exec Dt:

03/05/2025

Assignee

BIOPHARMA CREDIT PLC [COLLATERAL AGENT]

C/O BEAUFORT HOUSE, 51 NEW NORTH ROAD

EXETER, UNITED KINGDOM EX4 4EP

Correspondence name and address
	MUSSIE BEYENE
	AKIN GUMP STRAUSS HAUER & FELD LLP
	2001 K STREET N.W.
	WASHINGTON, DC 20006

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