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Reel/Frame:	021602/0423			Pages:	11
		Recorded:	09/29/2008
Attorney Dkt #:	D8022-00012
Conveyance:	SECURITY AGREEMENT

Total properties: 28

1

Patent #:	6752443	Issue Dt:	06/22/2004	Application #:	10009234	Filing Dt:	04/12/2002
Title:	LOAD FLOOR SYSTEM

2

Patent #:	NONE	Issue Dt:		Application #:	10062707	Filing Dt:	01/31/2002
Publication #:	US20020132257	Pub Dt:	09/19/2002
Title:	Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell

3

Patent #:	NONE	Issue Dt:		Application #:	10425006	Filing Dt:	04/28/2003
Publication #:	US20040180438	Pub Dt:	09/16/2004
Title:	Methods and compositions for silencing genes without inducing toxicity

4

Patent #:	NONE	Issue Dt:		Application #:	10513708	Filing Dt:	11/08/2004
Publication #:	US20060084617	Pub Dt:	04/20/2006
Title:	Methods for delivery of nucleic acids

5

Patent #:	NONE	Issue Dt:		Application #:	10522962	Filing Dt:	01/31/2005
Publication #:	US20050239728	Pub Dt:	10/27/2005
Title:	Double stranded rna structures and constructs, and methods for generating and using the same

6

Patent #:	NONE	Issue Dt:		Application #:	10531349	Filing Dt:	04/15/2005
Publication #:	US20060035344	Pub Dt:	02/16/2006
Title:	Double-stranded rna structures and constructs, and methods for generating and using the same

7

Patent #:	NONE	Issue Dt:		Application #:	10547256	Filing Dt:	05/12/2006
Publication #:	US20060263764	Pub Dt:	11/23/2006
Title:	Methods and constructs for evaluation of rnai targets and effector molecules

8

Patent #:	8350021	Issue Dt:	01/08/2013	Application #:	10560377	Filing Dt:	06/19/2006
Publication #:	US20080070854	Pub Dt:	03/20/2008
Title:	CONSERVED HBV AND HCV SEQUENCES USEFUL FOR GENE SILENCING

9

Patent #:	9051566	Issue Dt:	06/09/2015	Application #:	10762395	Filing Dt:	01/22/2004
Publication #:	US20040152117	Pub Dt:	08/05/2004
Title:	POST-TRANSCRIPTIONAL GENE SILENCING USING EXPRESSED DOUBLE STRANDED RNA

10

Patent #:	NONE	Issue Dt:		Application #:	10773735	Filing Dt:	02/06/2004
Publication #:	US20040138168	Pub Dt:	07/15/2004
Title:	Methods and compositions for inhibiting the function of polynucleotide sequences

11

Patent #:	NONE	Issue Dt:		Application #:	10780450	Filing Dt:	02/13/2004
Publication #:	US20040147476	Pub Dt:	07/29/2004
Title:	Methods and compositions for inhibiting the function of polynucleotide sequences

12

Patent #:	7527945	Issue Dt:	05/05/2009	Application #:	10829747	Filing Dt:	04/22/2004
Publication #:	US20050039224	Pub Dt:	02/17/2005
Title:	TRANSFECTION KINETICS AND STRUCTURAL PROMOTERS

13

Patent #:	NONE	Issue Dt:		Application #:	10836856	Filing Dt:	04/30/2004
Publication #:	US20040198690	Pub Dt:	10/07/2004
Title:	Methods and compositions for inhibiting the function of polynucleotide sequences

14

Patent #:	NONE	Issue Dt:		Application #:	10897361	Filing Dt:	07/22/2004
Publication #:	US20040266721	Pub Dt:	12/30/2004
Title:	Methods and compositions for inhibiting the function of polynucleotide sequences

15

Patent #:	NONE	Issue Dt:		Application #:	10912438	Filing Dt:	08/05/2004
Publication #:	US20050004067	Pub Dt:	01/06/2005
Title:	Methods and compositions for inhibiting the function of polynucleotide sequences

16

Patent #:	NONE	Issue Dt:		Application #:	10916043	Filing Dt:	08/11/2004
Publication #:	US20050043267	Pub Dt:	02/24/2005
Title:	Methods and compositions for inhibiting the function of polynucleotide sequences

17

Patent #:	NONE	Issue Dt:		Application #:	10920965	Filing Dt:	08/18/2004
Publication #:	US20050054603	Pub Dt:	03/10/2005
Title:	Methods and compositions for inhibiting the function of polynucleotide sequences

18

Patent #:	NONE	Issue Dt:		Application #:	10949845	Filing Dt:	09/24/2004
Publication #:	US20050064496	Pub Dt:	03/24/2005
Title:	Methods and compositions for inhibiting the function of polynucleotide sequences

19

Patent #:	NONE	Issue Dt:		Application #:	10977537	Filing Dt:	10/29/2004
Publication #:	US20050239202	Pub Dt:	10/27/2005
Title:	Methods and compositions for inhibiting the function of polynucleotide sequences

20

Patent #:	NONE	Issue Dt:		Application #:	11333672	Filing Dt:	01/17/2006
Publication #:	US20060104956	Pub Dt:	05/18/2006
Title:	Methods and compositions for inhibiting the function of polynucleotide sequences

21

Patent #:	NONE	Issue Dt:		Application #:	11542291	Filing Dt:	10/03/2006
Publication #:	US20070027103	Pub Dt:	02/01/2007
Title:	Methods and compositions for silencing genes without inducing toxicity

22

Patent #:	NONE	Issue Dt:		Application #:	11606550	Filing Dt:	11/30/2006
Publication #:	US20080081792	Pub Dt:	04/03/2008
Title:	Methods and compositions for inhibiting the function of polynucleotide sequences

23

Patent #:	NONE	Issue Dt:		Application #:	11606590	Filing Dt:	11/30/2006
Publication #:	US20070238178	Pub Dt:	10/11/2007
Title:	Methods and compositions for inhibiting the function of polynucleotide sequences

24

Patent #:	NONE	Issue Dt:		Application #:	11638734	Filing Dt:	12/14/2006
Publication #:	US20070219151	Pub Dt:	09/20/2007
Title:	Methods and compositions for inhibiting the function of polynucleotide sequences

25

Patent #:	NONE	Issue Dt:		Application #:	11638809	Filing Dt:	12/14/2006
Publication #:	US20070232557	Pub Dt:	10/04/2007
Title:	Methods and compositions for inhibiting the function of polynucleotide sequences

26

Patent #:	7985581	Issue Dt:	07/26/2011	Application #:	11660937	Filing Dt:	03/09/2009
Publication #:	US20090298909	Pub Dt:	12/03/2009
Title:	MULTIPLE RNA POLYMERASE III PROMOTER EXPRESSION CONSTRUCTS

27

Patent #:	7897382	Issue Dt:	03/01/2011	Application #:	12034541	Filing Dt:	02/20/2008
Publication #:	US20090081654	Pub Dt:	03/26/2009
Title:	TRANSFECTION KINETICS AND STRUCTURAL PROMOTERS

28

Patent #:	NONE	Issue Dt:		Application #:	12106649	Filing Dt:	04/21/2008
Publication #:	US20080194514	Pub Dt:	08/14/2008
Title:	Methods and Compositions for Inhibiting the Function of Polynucleotide Sequences

Assignor

1

NUCLEONICS, INC.

Exec Dt:

07/11/2008

Assignees

1

NEW ENTERPRISE ASSOCIATES 10, LIMITED PARTNERSHIP

1119 ST. PAUL STREET

BALTIMORE, MARYLAND 21202

2

S.R. ONE, LIMITED

161 WASHINGTON STREET

SUITE 500, EIGHT TOWER BRIDGE

CONSHOHOCKEN, PENNSYLVANIA 19428-2077

3

C/O ODLANDER, FREDRIKSON & CO AB

STRANDVAGEN 5B

STOCKHOLM, SWEDEN SE-114 51

4

HEALTHCAP IV KB

STRANDVAGEN 5B

STOCKHOLM, SWEDEN SE-114 51

5

HEALTHCAP IV, L.P.

C/O HEALTH CAP IV, GP S.A.

18 AVENUE D'OUCHY

LAUSANNE, SWITZERLAND CH-1006

6

HEALTHCAP IV BIS, L.P.

C/O HEALTH CAP IV, GP S.A.

18 AVENUE D'OUCHY

LAUSANNE, SWITZERLAND CH-1006

7

BURRILL LIFE SCIENCES CAPITAL FUND, L.P.

ONE EMBARCADERO CENTER, SUITE 2700

SAN FRANCISCO, CALIFORNIA 94111

8

BURRILL INDIANA LIFE SCIENCES CAPITAL FUND, L.P.

ONE EMBARCADERO CENTER, SUITE 2700

SAN FRANCISCO, CALIFORNIA 94111

9

QUAKER BIOVENTURES, L.P.

CIRA CENTRE, 2929 ARCH STREET

PHILADELPHIA, PENNSYLVANIA 19104-2868

10

QUAKER BIOVENTURES TOBACCO FUND, L.P.

CIRA CENTRE, 2929 ARCH STREET

PHILADELPHIA, PENNSYLVANIA 19104-2868

11

POSCO BIOVENTURES I, L.P.

2121 PALOMAR AIRPORT ROAD, SUITE 300

CARLSBAD, CALIFORNIA 92009

Correspondence name and address
	SAMUEL W. APICELLI
	DUANE MORRIS LLP
	30 S 17TH STREET
	PHILADELPHIA, PA 19103

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